Caruncular lesions in Denmark 1978–2002: a histopathological study with correlation to clinical referral diagnosis
Article first published online: 1 SEP 2005
Acta Ophthalmologica Scandinavica
Volume 84, Issue 1, pages 130–136, February 2006
How to Cite
Østergaard, J., Prause, J. U. and Heegaard, S. (2006), Caruncular lesions in Denmark 1978–2002: a histopathological study with correlation to clinical referral diagnosis. Acta Ophthalmologica Scandinavica, 84: 130–136. doi: 10.1111/j.1600-0420.2005.00543.x
- Issue published online: 1 SEP 2005
- Article first published online: 1 SEP 2005
- Received on March 21st, 2005. Accepted on July 5th, 2005.
Purpose: To carry out a retrospective clinicopathological evaluation of caruncular lesions.
Methods: Data were collected from all surgically removed and histopathologically evaluated caruncular lesions registered by Danish pathology departments during the 25-year period 1978–2002.
Results: A total of 574 caruncular lesions were identified. The number of caruncular lesions increased significantly during the 25-year period. This was due to an increase in the number of benign lesions, whereas the number of premalignant and malignant lesions remained constant. A total of 550 (96%) of the lesions were benign. Naevus (n = 248, 43%) and papilloma (n = 131, 23%) were the most common neoplasms. Premalignant lesions (n = 10, 1.7%) were dominated by primary acquired melanosis (PAM) with atypia and epithelial dysplasia. Malignant lesions constituted a total of 14 neoplasms (2.4%), with basal cell carcinoma (n = 4, 0.7%) and lymphoma (n = 4, 0.7%) being the most frequent. The preoperative clinical diagnosis was correct in 286 (50%) of cases.
Conclusion: Caruncular lesions are predominately benign but the lesions are rare and diverse, making clinical diagnosis difficult. Referral of excised lesions for pathological examination is recommended.