Platelet paroxetine binding in depressed and nondepressed chronic pain patients


*Laboratory of Neuropsychiatry, University Hospital, Rigshospitalet – 6102, DK-2100 Copenhagen Ø, Denmark


Analysis of 3H-paroxetine binding was used to determine the number of serotonin transporters in platelet membranes of chronic pain patients and controls. The pain patients who also suffered from depression in addition to the pain had significantly more serotonin transporters than the controls.