Is depression related to subsequent diabetes mellitus?

  1. M. van den Akker1,
  2. A. Schuurman1,
  3. J. Metsemakers1,
  4. F. Buntinx1,2

Article first published online: 29 JUL 2004

DOI: 10.1111/j.1600-0447.2004.00333.x

Issue

Acta Psychiatrica Scandinavica

Acta Psychiatrica Scandinavica

Volume 110, Issue 3, pages 178–183, September 2004

Additional Information

How to Cite

van den Akker, M., Schuurman, A., Metsemakers, J. and Buntinx, F. (2004), Is depression related to subsequent diabetes mellitus?. Acta Psychiatrica Scandinavica, 110: 178–183. doi: 10.1111/j.1600-0447.2004.00333.x

Author Information

  1. 1

    Department of General Practice, Maastricht University, Maastricht, the Netherlands

  2. 2

    Department of General Practice, Catholic University of Leuven, Leuven, Belgium

*Marjan van den Akker, Department of General Practice Maastricht University, PO Box 616, 6200 MD Maastricht, the Netherlands. Tel.: +31 43 388 2321; E-mail: marjan.vandenakker@hag.unimaas.nl

Publication History

  1. Issue published online: 29 JUL 2004
  2. Article first published online: 29 JUL 2004
  3. Accepted for publication February 24, 2004

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Keywords:

  • depressive disorder;
  • diabetes mellitus;
  • epidemiologic research design;
  • general practice

Objective:  To compare the risk of developing diabetes mellitus (DM) in the general population between subjects who had a depression and subjects who never had a depression.

Method: Retrospective cohort design. People with depression were diagnosed with a depression between 1975 and 1990; controls never had a depression. Both groups were followed for a diagnosis of type II diabetes until 2000. Data on 1334 depressed and 66 670 non-depressed subjects were available from a large general practice-based database.

Results:  No overall relation was found, but among males below age 50 there was a 78% increase in the rate of development of DM compared with non-depressed patients (hazard ratio 1.78, 95% CI: 1.21–2.62).

Conclusion:  Depression in males between the age of 20 and 50 years is related to an increased risk of developing DM.

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