Prevalence of bipolar disorder in the general population: a Reappraisal Study of the Netherlands Mental Health Survey and Incidence Study
Article first published online: 6 SEP 2004
Acta Psychiatrica Scandinavica
Volume 110, Issue 5, pages 374–382, November 2004
How to Cite
Regeer, E. J., Ten Have, M., Rosso, M. L., Hakkaart-van Roijen, L., Vollebergh, W. and Nolen, W. A. (2004), Prevalence of bipolar disorder in the general population: a Reappraisal Study of the Netherlands Mental Health Survey and Incidence Study. Acta Psychiatrica Scandinavica, 110: 374–382. doi: 10.1111/j.1600-0447.2004.00363.x
- Issue published online: 6 SEP 2004
- Article first published online: 6 SEP 2004
- Accepted for publication March 22, 2004
- bipolar disorder;
Objective: The Netherlands Mental Health Survey and Incidence Study (NEMESIS) is a Dutch population study using a fully structured interview (Composite International Diagnostic Interview, CIDI), administered by trained interviewers. Based on all three assessments of NEMESIS, 2.4% of the respondents were identified with lifetime bipolar disorder (DSM-III-R).
The primary aim of the study was to estimate the prevalence of bipolar disorder in the same population based on a semistructured interview administered by clinicians.
Method: Seventy-four persons identified with a lifetime CIDI/DSM-III-R bipolar disorder and 40 persons with a major depressive disorder (MDD) were reinterviewed with the Structured Clinical Interview for DSM (SCID).
Results: Based on the SCID, 30 of 74 respondents with a CIDI/DSM-III-R bipolar disorder and eight of 40 respondents with MDD met DSM-IV criteria for bipolar disorder or cyclothymia, corresponding with an adjusted lifetime prevalence in these groups of 1% (95% CI: 0.7–1.3%) and 4.2% (95% CI: 1.6–6.9%) respectively.
Conclusion: Compared with the SCID, the CIDI on the one hand overdiagnoses bipolar disorder but on the other hand underdiagnoses bipolar disorder.