Patterns, predictors and impact of substance use in early psychosis: a longitudinal study
Article first published online: 6 OCT 2006
Acta Psychiatrica Scandinavica
Volume 115, Issue 4, pages 304–309, April 2007
How to Cite
Addington, J. and Addington, D. (2007), Patterns, predictors and impact of substance use in early psychosis: a longitudinal study. Acta Psychiatrica Scandinavica, 115: 304–309. doi: 10.1111/j.1600-0447.2006.00900.x
- Issue published online: 13 MAR 2007
- Article first published online: 6 OCT 2006
- Accepted for publication August 23, 2006
Objective: The purpose was to determine the prevalence of substance use and its impact on outcome 3 years after presentation for a first-episode of psychosis.
Method: Subjects were 203 consecutive admissions to an early psychosis program. Assessments included substance use, positive, negative and depressive symptoms and social functioning. Assessments occurred at baseline, and 1-, 2- and 3-year follow-ups.
Results: The prevalence of substance misuse was high with 51% having a substance use disorder (SUD), 33% with cannabis SUD and 35% with an alcohol SUD. Numbers with an alcohol SUD declined considerably by 1 year and for cannabis SUD by 2 years. Substance misuse was significantly associated with male gender, young age and age of onset and cannabis misuse with increased positive symptoms.
Conclusion: This study confirms the high rates of substance misuse, in particular cannabis, in first-episode psychosis. It further demonstrates that these rates can be reduced.