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Keywords:

  • bipolar disorder;
  • mood ratings;
  • measurement;
  • bipolar disorder;
  • depression;
  • hypomania;
  • impairment

Objective:  Traditional cross-sectional clinician-rated measures have limited use in clinical trials of bipolar disorder. We examine the validity and usefulness of patients’ daily ratings of mood and functional impairment during a treatment trial.

Method:  Ten subjects with bipolar II disorder completed daily ratings of depression severity, depression, hypomania and functional impairment over a 9-month trial. Ratings were correlated with clinician-rated measures at nine time points to determine validity. Mood ratings were contrasted with cross-sectional data for one subject to determine usefulness of such fine-grained data.

Results:  Moderate to large correlations were found between patients’ and clinicians' ratings of mood and impairment for most of the nine time points. The utility of the patients’ ratings relative to clinician-rated cross-sectional measures was also illustrated.

Conclusion:  Results support the validity and usefulness of patients’ daily mood ratings.