Cognitive-behavioural therapy for late-life anxiety disorders: a systematic review and meta-analysis
Article first published online: 28 JUN 2008
Copyright © 2008 The Authors. Journal Compilation © 2008 Blackwell Munksgaard
Acta Psychiatrica Scandinavica
Volume 117, Issue 6, pages 403–411, June 2008
How to Cite
Hendriks, G. J., Oude Voshaar, R. C., Keijsers, G. P. J., Hoogduin, C. A. L. and Van Balkom, A. J. L. M. (2008), Cognitive-behavioural therapy for late-life anxiety disorders: a systematic review and meta-analysis. Acta Psychiatrica Scandinavica, 117: 403–411. doi: 10.1111/j.1600-0447.2008.01190.x
- Issue published online: 28 JUN 2008
- Article first published online: 28 JUN 2008
- Accepted for publication March 26, 2008
- anxiety disorders;
- cognitive therapy
Objective: To examine and estimate the efficacy of cognitive-behavioural therapy (CBT) for late-life anxiety disorders.
Method: A systematic review and meta-analysis of randomized controlled trials comparing CBT with i) a waiting-list control condition and ii) an active control condition controlling for non-specific effects in patients aged over 60 years and suffering from an anxiety disorder. The main outcome parameter of individual studies, i.e. effect on anxiety, was pooled using the standardized mean difference (SMD).
Results: Seven papers fulfilled the inclusion criteria, including nine randomized controlled comparisons for 297 patients. Anxiety symptoms were significantly more reduced following CBT than after either a waiting-list control condition [SMD = −0.44 (95 CI: −0.84 −0.04), P = 0.03] or an active control condition [SMD = −0.51 (95 CI: −0.81, −0.21), P<0.001]. Additionally, CBT significantly alleviated accompanying symptoms of worrying and depression.
Conclusion: Cognitive-behavioural therapy is efficacious for the treatment of late-life anxiety disorders.