Indicators of pretreatment suicidal ideation in adults with major depressive disorder
Article first published online: 2 DEC 2009
© 2009 John Wiley & Sons A/S
Acta Psychiatrica Scandinavica
Volume 121, Issue 6, pages 480–484, June 2010
How to Cite
Morris, D. W., Trivedi, M. H., Husain, M. M., Fava, M., Budhwar, N., Wisniewski, S. R., Miyahara, S., Gollan, J. K., Davis, L. L., Daly, E. J. and Rush, A. J. (2010), Indicators of pretreatment suicidal ideation in adults with major depressive disorder. Acta Psychiatrica Scandinavica, 121: 480–484. doi: 10.1111/j.1600-0447.2009.01516.x
- Issue published online: 4 MAY 2010
- Article first published online: 2 DEC 2009
- Accepted for publication November 6, 2009
- suicidal ideation;
- major depressive disorder;
- mood disorder
Morris DW, Trivedi MH, Husain MM, Fava M, Budhwar N, Wisniewski SR, Miyahara S, Gollan JK, Davis LL, Daly EJ, Rush AJ. Indicators of pretreatment suicidal ideation in adults with major depressive disorder.
Objective: In order to evaluate the presence of treatment emergent suicidal ideation (SI), it becomes necessary to identify those patients with SI at the onset of treatment. The purpose of this report is to identify sociodemographic and clinical features that are associated with SI in major depressive disorder (MDD) patients prior to treatment with a selective serotonin reuptake inhibitor.
Method: This multisite study enrolled 265 out-patients with non-psychotic MDD. Sociodemographic and clinical features of participants with and without SI were compared post hoc.
Results: Social phobia, bulimia nervosa, number of past depressive episodes, and race were independently associated with SI by one or more SI measure.
Conclusion: Concurrent social phobia and bulimia nervosa may be potential risk factors for SI in patients with non-psychotic MDD. Additionally, patients with more than one past depressive episode may also be at increased risk of SI.