Experience of trauma and conversion to psychosis in an ultra-high-risk (prodromal) group
Version of Record online: 25 FEB 2010
© 2010 John Wiley & Sons A/S
Acta Psychiatrica Scandinavica
Volume 121, Issue 5, pages 377–384, May 2010
How to Cite
Bechdolf, A., Thompson, A., Nelson, B., Cotton, S., Simmons, M. B., Amminger, G. P., Leicester, S., Francey, S. M., McNab, C., Krstev, H., Sidis, A., McGorry, P. D. and Yung, A. R. (2010), Experience of trauma and conversion to psychosis in an ultra-high-risk (prodromal) group. Acta Psychiatrica Scandinavica, 121: 377–384. doi: 10.1111/j.1600-0447.2010.01542.x
- Issue online: 13 APR 2010
- Version of Record online: 25 FEB 2010
- Accepted for publication January 14, 2010
Bechdolf A, Thompson A, Nelson B, Cotton S, Simmons MB, Amminger GP, Leicester S, Francey SM, McNab C, Krstev H, Sidis A, McGorry PD, Yung AR. Experience of trauma and conversion to psychosis in an ultra-high-risk (prodromal) group.
Objective: We aimed to replicate a recent finding of high prevalence of trauma history in patients at ‘ultra-high risk’ (UHR) of psychotic disorder and to investigate whether trauma predicts conversion to psychosis in this population.
Method: A consecutive sample of UHR patients was assessed. History of trauma was accessed with the General Trauma Questionnaire. Cox regression models were used to explore relationship between conversion to psychosis and trauma.
Results: Of 92 UHR patients nearly 70% had experienced a traumatic event and 21.7% developed psychosis during follow-up (mean 615 days). Patients who had experienced a sexual trauma (36%) were significantly more likely to convert to first-episode psychosis (OR 2.96) after controlling for meeting multiple UHR intake groups.
Conclusion: UHR patients have a high prevalence of history of trauma. Previous sexual trauma may be a predictor of onset of psychotic disorder in this population.