Borderline personality disorder traits and their relationship with dimensions of normative personality: a web-based cohort and twin study
Article first published online: 28 DEC 2010
© 2010 John Wiley & Sons A/S
Acta Psychiatrica Scandinavica
Volume 123, Issue 5, pages 349–359, May 2011
How to Cite
Kendler, K. S., Myers, J. and Reichborn-Kjennerud, T. (2011), Borderline personality disorder traits and their relationship with dimensions of normative personality: a web-based cohort and twin study. Acta Psychiatrica Scandinavica, 123: 349–359. doi: 10.1111/j.1600-0447.2010.01653.x
- Issue published online: 14 APR 2011
- Article first published online: 28 DEC 2010
- Accepted for publication November 16, 2010
- borderline personality disorder;
Kendler KS, Myers J, Reichborn-Kjennerud T. Borderline personality disorder traits and their relationship with dimensions of normative personality: a web-based cohort and twin study.
Objective: To describe the structure of genetic and environmental risk factors for four dimensions of borderline personality disorder (BPD) and to understand the source of resemblance of these dimensions and normal personality.
Method: A web-based sample (n = 44,112 including 542 twin pairs) completed items from 4 scales of the Dimensional Assessment of Personality Pathology Basic Questionnaire and the Big Five Inventory.
Results: A one-factor common pathway model best fits the 4 BPD scales producing a highly heritable latent liability (heritability = 60%) and strong loadings on all 4 dimensions. Affective instability had the lowest trait-specific genetic loading, suggesting that it was a core feature of BPD. A complex pattern of genetic and environmental associations was found between the big five personality traits and BPD dimensions. The strongest genetic correlations with the BPD traits were generally seen for neuroticism (positive), followed by conscientiousness and agreeableness, both negative.
Conclusion: In the general population, these four BPD dimensions reflect one underlying highly heritable factor. The association between normative personality and dimensions of BPD is complex with high degrees of genetic correlation.