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Keywords:

  • Prostate;
  • nonspecific granulomatous prostatitis;
  • calculosis;
  • ductal ectasia;
  • eosinophilic metaplasia;
  • Paneth cell-like metaplasia

We present a case of nonspecific granulomatous prostatitis in combination with calculous ductal ectasia and extensive epithelial Paneth cell-like metaplasia in a TURP-specimen. Our report highlights the importance of calculous ductal obstruction and stasis of secretions in the etiopathogenesis of this type of prostatitis. The observed extensive Paneth cell-like metaplastic change in adjacent epithelial cells most likely represents a phenotypic adaptive mechanism directed against foreign antigens and nondegradable lipids in the stagnant intraluminal debris.