Received 16 February 2005.
Nonspecific granulomatous prostatitis with calculous ductal ectasia and extensive Paneth cell-like epithelial metaplasia†
Article first published online: 28 JUL 2005
Volume 113, Issue 7-8, pages 564–567, August 2005
How to Cite
DIKOV, D., VASSILEV, I. and DIMITRAKOV, J. (2005), Nonspecific granulomatous prostatitis with calculous ductal ectasia and extensive Paneth cell-like epithelial metaplasia. APMIS, 113: 564–567. doi: 10.1111/j.1600-0463.2005.apm_215.x
Accepted 13 May 2005.
- Issue published online: 28 JUL 2005
- Article first published online: 28 JUL 2005
- nonspecific granulomatous prostatitis;
- ductal ectasia;
- eosinophilic metaplasia;
- Paneth cell-like metaplasia
We present a case of nonspecific granulomatous prostatitis in combination with calculous ductal ectasia and extensive epithelial Paneth cell-like metaplasia in a TURP-specimen. Our report highlights the importance of calculous ductal obstruction and stasis of secretions in the etiopathogenesis of this type of prostatitis. The observed extensive Paneth cell-like metaplastic change in adjacent epithelial cells most likely represents a phenotypic adaptive mechanism directed against foreign antigens and nondegradable lipids in the stagnant intraluminal debris.