No link between rosacea and Propionibacterium acnes
Article first published online: 18 MAY 2012
© 2012 The Authors APMIS © 2012 APMIS
Volume 120, Issue 11, pages 922–925, November 2012
How to Cite
Jahns AC, Lundskog B, Dahlberg I, Curiche Tamayo N, McDowell A, Patrick S, Alexeyev OA. No link between Rosacea and Propionibacterium acnes. APMIS 2012.
- Issue published online: 26 SEP 2012
- Article first published online: 18 MAY 2012
- Manuscript Accepted: 15 APR 2012
- Manuscript Received: 4 JAN 2012
- Umeå University
- Västerbotten County Council
- Propionibacterium acnes;
Rosacea is a common skin disease in adults affecting mainly the facial skin. Although inflammation appears to play a pathogenic role in rosacea, initiating factors are largely unknown. Microbial involvement in the development of rosacea has been suggested previously. We aimed to visualize Propionibacterium acnes in the skin compartments of rosacea patients. Facial skin biopsies from 82 rosacea patients and 25 controls were stained with a P. acnes-specific monoclonal antibody (QUBPa3). Seven of 82 patients (8.5%) tested positive for P. acnes which was present either as a biofilm (57% of positive) or a microcolony (43%) in colonized patients. Our results suggest that P. acnes does not play a major role in the pathogenesis of rosacea.