Contact allergens in toothpastes and a review of their hypersensitivity

  1. Eeva-Liisa Sainio1,
  2. Lasse Kanerva2,*

Article first published online: 11 APR 2006

DOI: 10.1111/j.1600-0536.1995.tb00509.x

Issue

Contact Dermatitis

Contact Dermatitis

Volume 33, Issue 2, pages 100–105, August 1995

Additional Information

How to Cite

Sainio, E.-L. and Kanerva, L. (1995), Contact allergens in toothpastes and a review of their hypersensitivity. Contact Dermatitis, 33: 100–105. doi: 10.1111/j.1600-0536.1995.tb00509.x

Author Information

  1. 1

    Product Safety Unit. National Consumer Administration, Haapaniemenkatu 4, FIN-00530 Helsinki, Finland

  2. 2

    Section of Dermatology, Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, FIN-00250 Helsinki, Finland

*L. Kanerva, Section of Dermatology, Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, FIN-00250 Helsinki, Finland

Publication History

  1. Issue published online: 11 APR 2006
  2. Article first published online: 11 APR 2006
  3. Accepted for publication 30 September 1994

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Keywords:

  • toothpaste;
  • immediate allergy;
  • contact allergens;
  • stomatitis;
  • cheilitis;
  • cinnamic aldehyde;
  • flavours;
  • fluorides;
  • cosmetics and toiletries;
  • product ingredient labelling

The present study summarizes information on toothpaste composition as supplied by the manufacturers. The survey covered 48 items, virtually all toothpastes offered for sale in Finland. It was concluded that the toothpastes are not entirely safe to use, because almost 50% of the products studied contained a total of some 30 compounds widely recognized as allergens. According to the literature, the most common allergens in toothpastes are flavours (e.g., cinnamic aldehyde, cinnamon oil and peppermint) and preservatives. Symptoms include stomatitis, cheilitis. glossitis, gingivitis, perioral dermatitis and immediate hypersensitivity.

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