W.U. has accepted honoraria for presentations or travel reimbursement for cosmetic industry association meetings from these associations. A.S. works as consultant for cosmetic industry (associations). E.S. previously worked for Kurt Kitzing GmbH, Wallerstein, Germany.
Contact sensitization to tree moss (Evernia furfuracea extract, INCI) is heterogeneous
Article first published online: 4 APR 2012
© 2012 John Wiley & Sons A/S
Volume 67, Issue 1, pages 36–41, July 2012
How to Cite
Uter, W., Schmidt, E., Lessmann, H. and Schnuch, A. (2012), Contact sensitization to tree moss (Evernia furfuracea extract, INCI) is heterogeneous. Contact Dermatitis, 67: 36–41. doi: 10.1111/j.1600-0536.2012.02064.x
- Issue published online: 9 JUN 2012
- Article first published online: 4 APR 2012
- Accepted for publication 1 February 2012
- contact allergy;
- Evernia furfuracea (CAS 68648-41-9;
- tree moss);
- Evernia prunastri (CAS 90028-68-5 or 68917-10-2;
- oak moss)
Background. Evernia prunastri (oak moss) and Evernia furfuracea (tree moss) are lichens from which natural extracts are obtained.
Objectives. To identify possible subgroups of E. furfuracea-sensitized patients according to whether these are allergic to lichen components or to contaminants.
Methods. A retrospective analysis was performed of surveillance data collected by the Information Network of Departments of Dermatology (www.ivkd.org) in 2003–2010 with oak moss absolute (1% pet.), tree moss absolute (1% pet.), and colophonium (colophony, 20% pet.).
Results. In total, 3030 patients had been tested with all three allergens. Positive reactions to E. furfuracea were observed in 6.37%, to E. prunastri in 5.71%, and to colophonium in 4.82%. Concordance between positive reactions to E. prunastri and E. furfuracea was good only in patients not co-sensitized to colophonium (Cohen's κ = 0.681, 95% confidence interval 0.615-0.746). Moreover, E. furfuracea-sensitized patients showed (strong or extreme) concomitant reactions to colophonium significantly more often if not co-sensitized to E. prunastri.
Conclusions. Two subgroups of E. furfuracea-sensitized patients are identifiable: (i) those with sensitization to (oxidized) resin acids, as indicated by positive patch test reactions also to colophonium, and (ii) those non-sensitized to resin acids, but sensitized to common constituents of E. prunastri and E. furfuracea.