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“Lumpy-Bumpy” Elastic Fibers in the Skin and Lungs of a Patient with a Penicillamine-Induced Elastosis Perforans Serpiginosa
Article first published online: 27 APR 2006
DOI: 10.1111/j.1600-0560.1979.tb01131.x
1600-0560/asset/cover.gif?v=1&s=f6b47251a0e8f5ca97a82a31a245bb08b87bad96 "Journal of Cutaneous Pathology")
Additional Information
How to Cite
BARDACH, H., GEBHART, W. and NIEBAUER, G. (1979), “Lumpy-Bumpy” Elastic Fibers in the Skin and Lungs of a Patient with a Penicillamine-Induced Elastosis Perforans Serpiginosa. Journal of Cutaneous Pathology, 6: 243–252. doi: 10.1111/j.1600-0560.1979.tb01131.x
Publication History
- Issue published online: 27 APR 2006
- Article first published online: 27 APR 2006
- (Received for publication November 14, 1978)
- Abstract
- References
- Cited By
Penicillamine-induced cutaneous elastosis perforans serpiginosa associated with a large air-cyst in the right lung is described in a 29-year-old female patient with Wilson disease. Identical light and electron-microscopic changes were present in both dermal and pulmonary elastic tissue, suggesting a disseminated drug-induced cutaneo-visceral elastosis. Lung cysts have not been previously reported in association with long term penicillamine treatment. The electron-microscopic morphology of the elastic fibers was found to be “specific” enough to allow separation of penicillamine-induced elastosis perforans serpiginosa from other forms of this disease.