Get access

Epithelioid fibrous papule – a new variant


Cynthia Kucher, Department of Pathology, Greenwich Hospital, 5 Perryridge Road, Greenwich, CT, USA
Tel: +1 203 863 3769
Fax: +1 203 863 3846


Fibrous papules (FPs) are common benign lesions occurring most frequently on the nose. Multiple variants have been described, including classic, hypercellular, clear cell, pigmented, pleomorphic, inflammatory and granular FPs. We describe a group of FPs with characteristics that do not easily fit into any of the above categories, with diffuse sheets of distinctive epithelioid cells, causing potential diagnostic confusion. Immunoperoxidase stains show that the cells of this ‘epithelioid fibrous papule’ are reactive for procollagen, and are negative for NKI/C3, unlike previously described clear cell variants.