• 1
    Aszterbaum M, Epstein J, Oro A, et al. Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice. Nat Med 1999; 5: 1285.
  • 2
    Madan V, Hoban P, Strange RC, et al. Genetics and risk factors for basal cell carcinoma. Br J Dermatol 2006; 154(Suppl. 1): 5.
  • 3
    Wong CS, Strange RC, Lear JT. Basal cell carcinoma. BMJ 2003; 327: 794.
  • 4
    Athar M, Tang X, Lee JL, et al. Hedgehog signaling in skin development and cancer. Exp Dermatol 2006; 15: 667.
  • 5
    Gailani MR, Leffell DJ, Ziegler A, et al. Relationship between sunlight exposure and a key genetic alteration in basal cell carcinoma. J Natl Cancer Inst 1996; 88: 349.
  • 6
    Crowson AN. Basal cell carcinoma: biology, morphology and clinical implications. Mod Pathol 2006; 19(Suppl. 2): 127.
  • 7
    High A, Zedan W. Basal cell nevus syndrome. Curr Opin Oncol 2005; 17: 160.
  • 8
    St-Jacques B, Dassule HR, Karavanova I, et al. Sonic hedgehog signaling is essential for hair development. Curr Biol 1998; 8: 1058.
  • 9
    Chiang C, Swan RZ, Grachtchouk M, et al. Essential role for Sonic hedgehog during hair follicle morphogenesis. Dev Biol 1999; 205: 1.
  • 10
    Sato N, Leopold PL, Crystal RG. Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog. J Clin Invest 1999; 104: 855.
  • 11
    Nilsson M, Unden AB, Krause D, et al. Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1. Proc Natl Acad Sci U S A 2000 28; 97: 3438.
  • 12
    Hutchin ME, Kariapper MS, Grachtchouk M, et al. Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle. Genes Dev 2005; 19: 214.
  • 13
    Grachtchouk M, Mo R, Yu S, et al. Basal cell carcinomas in mice overexpressing Gli2 in skin. Nat Genet 2000; 24: 216.
  • 14
    Wegner M. From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res 1999; 27: 1409.
  • 15
    Vidal VP, Chaboissier MC, Lutzkendorf S, et al. Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment. Curr Biol 2005; 15: 1340.
  • 16
    Stolt CC, Lommes P, Sock E, et al. The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev 2003; 17: 1677.
  • 17
    Obaidat NA, Alsaad KO, Obaidat NA, et al. Skin adnexal neoplasms-part 2: an approach to tumours of cutaneous sweat glands. J Clin Pathol 2007; 60: 145.
  • 18
    Robson A, Greene J, Ansari N, et al. Eccrine porocarcinoma (malignant eccrine poroma): a clinicopathologic study of 69 cases. Am J Surg Pathol 2001; 25: 710.
  • 19
    Alsaad KO, Obaidat NA, Ghazarian D. Skin adnexal neoplasms-part 1: an approach to tumours of the pilosebaceous unit. J Clin Pathol 2007; 60: 129.
  • 20
    Dong C, Wilhelm D, Koopman P. Sox genes and cancer. Cytogenet Genome Res 2004; 105: 442.
  • 21
    Kordes U, Hagel C. Expression of SOX9 and SOX10 in central neuroepithelial tumor. J Neurooncol 2006; 80: 151.
  • 22
    Wang H, McKnight NC, Zhang T, et al. SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells. Cancer Res 2007; 67: 528.
  • 23
    Zhao C, Bratthauer GL, Barner R, Vang R. Immunohistochemical analysis of sox9 in ovarian Sertoli cell tumors and other tumors in the differential diagnosis. Int J Gynecol Pathol 2007; 26: 1.
  • 24
    Saldanha G, Fletcher A, Slater DN. Basal cell carcinoma: a dermatopathological and molecular biological update. Br J Dermatol 2003; 148: 195.
  • 25
    Zalaudek I, Ferrara G, Broganelli P, et al. Dermoscopy patterns of fibroepithelioma of pinkus. Arch Dermatol 2006; 142: 1318.
  • 26
    Kurzen H, Esposito L, Langbein, et al. Cytokeratins as markers of follicular differentiation: an immunohistochemical study of trichoblastoma and basal cell carcinoma. Am J Dermatopathol 2001; 23: 501.
  • 27
    Yamamoto O, Asahi M. Cytokeratin expression in trichoblastic fibroma (small nodular type trichoblastoma), trichoepithelioma and basal cell carcinoma. Br J Dermatol 1999; 140: 8.
  • 28
    Brownstein MH, Shapiro L. Trichilemmoma. Analysis of 40 new case. Arch Dermatol 1973; 107: 866.
  • 29
    Kurokawa I, Nishijima S, Kusumoto K, et al. Trichilemmoma: an immunohistochemical study of cytokeratins. Br J Dermatol 2003; 149: 99.
  • 30
    Dahmane N, Lee J, Robins P, et al. Activation of the transcription factor Gli1 and the Sonic hedgehog signaling pathway in skin tumours. Nature 1997; 389: 876.
  • 31
    Allen M, Grachtchouk M, Sheng H, et al. Hedgehog signaling regulates sebaceous gland development. Am J Pathol 2003; 163: 2173.
  • 32
    Niemann C, Unden AB, Lyle S, et al. Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis. Proc Natl Acad Sci U S A 2003; 100: 11873.
  • 33
    Wehrli BM, Huang W, De Crombrugghe B, et al. Sox9, a master regulator of chondrogenesis, distinguishes mesenchymal chondrosarcoma from other small blue round cell tumors. Hum Pathol 2003; 34: 263.