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Collagenous spherulosis in an oral mucous cyst

Authors


Klaus F. Helm, MD, Department of Dermatology, Pennsylvania State College of Medicine, Hershey, PA 17033, USA
Tel: +717 531 1677
Fax: +717 531 4278
e-mail: Khelm@psu.edu

Abstract

Collagenous spherulosis is a histological pattern that has been described in both benign and malignant salivary gland tumors, proliferative lesions of breast ductal epithelium, chondroid syringomas and schwannomas. Histologic structures of similar appearance have also been reported in oral extravasation mucoceles as questionable myxoglobulosis or myxoglobulosis-like change. We report collagenous spherulosis within a mucocele removed from the lower lip of a 17-year-old female. Based upon histologic appearance, immunophenotypic data and review of the literature, we hypothesize that collagenous spherulosis and myxoglobulosis are morphologically related reaction patterns.

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