The authors report no conflict of interest.
Tumors composed of malignant epithelial and melanocytic populations: a case series and review of the literature
Article first published online: 24 AUG 2008
© 2008 Blackwell Munksgaard
Journal of Cutaneous Pathology
Volume 36, Issue 2, pages 211–219, February 2009
How to Cite
Satter, E. K., Metcalf, J., Lountzis, N. and Elston, D. M. (2009), Tumors composed of malignant epithelial and melanocytic populations: a case series and review of the literature. Journal of Cutaneous Pathology, 36: 211–219. doi: 10.1111/j.1600-0560.2008.01000.x
The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, Department of Defense or the United States Government.
- Issue published online: 20 JAN 2009
- Article first published online: 24 AUG 2008
- Accepted for publication January 16, 2008
Over the last 30 years, there have been approximately 49 case reports of tumors composed of both malignant epithelial and malignant melanocytic populations. Herein, we present four additional cases of combined tumors that consist of two phenotypically distinct but intermingled populations of malignant cells. Each tumor was composed of an invasive melanoma closely associated with either a basal cell carcinoma or a squamous cell carcinoma. We review all previous case reports in the English literature and attempt to clarify the terminology and summarize what is currently known about these unique tumors.