Cutaneous and systemic plasmacytosis in an Asian male born in the North American continent: A controversial entity potentially related to multicentric Castleman disease

Authors

  • Brooke N. Shadel,

    1. Department of Dermatology, Saint Louis University School of Medicine, St Louis, MO, USA
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  • John L. Frater,

    1. Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
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  • Joshua D. G. Gapp,

    1. Department of Dermatology, Saint Louis University School of Medicine, St Louis, MO, USA
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  • M. Yadira Hurley

    Corresponding author
    1. Department of Dermatology, Saint Louis University School of Medicine, St Louis, MO, USA
      Dr Maria Yadira Hurley, Department of Dermatology, Saint Louis University School of Medicine, 1402 South Grand Boulevard, St Louis, MO 63104, USA
      Tel: (314) 256-3430
      Fax: (314) 256-3431
      e-mail: hurleyy@slu.edu
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Dr Maria Yadira Hurley, Department of Dermatology, Saint Louis University School of Medicine, 1402 South Grand Boulevard, St Louis, MO 63104, USA
Tel: (314) 256-3430
Fax: (314) 256-3431
e-mail: hurleyy@slu.edu

Abstract

Cutaneous and systemic plasmacytosis is a rare condition primarily affecting middle-aged individuals of Japanese descent and has principally been reported in cases originating from Asia. Its relationship, if any, to Castleman disease, is controversial. The authors report a case of cutaneous and systemic plasmacytosis involving a 36-year-old man of Chinese ancestry born in North America. The biopsy of an involved lymph node revealed changes resembling Castleman disease. Significantly, this case to our knowledge represents the first case of cutaneous and systemic plasmacytosis presenting in a patient of Chinese ancestry born on the North American mainland.

Shadel BN, Frater JL, Gapp JDG, Hurley MY. Cutaneous and systemic plasmacytosis in an Asian male born in the North American continent: A controversial entity potentially related to multicentric Castleman disease.

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