Mycosis fungoides exhibiting features of a dermatofibroma: a case report and review of the literature

Authors

  • Sarah M. Morcos,

    1. Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    2. Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
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  • Michael Girardi,

    1. Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
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  • Antonio Subtil,

    1. Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    2. Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
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  • Lynn D. Wilson,

    1. Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA
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  • Shawn E. Cowper

    Corresponding author
    1. Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    2. Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
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Shawn Cowper, MD, Departments of Dermatology and Pathology, Yale University School of Medicine, 15 York Street, LMP 5031, New Haven, CT 06520-8059, USA
Tel: +1 203 785 3524
Fax: +1 203 737 4307
e-mail: shawn.cowper@yale.edu

Abstract

We present the case of a 60-year-old male with known stage IA mycosis fungoides (MF) who developed a suspicious tumor within a pre-existing lymphomatous plaque of the right forearm. Microscopy revealed an unusual mixed fibrohistiocytic proliferation as well as atypical intraepidermal and dermal lymphocytes. There was no evidence of large-cell transformation. Histopathological, immunohistochemical and clinical clues suggest this lesion might not have represented a dermatofibroma, but rather a hitherto unreported dermatofibroma-like process arising within a lesion of MF. The potential impact of this atypical lesion on the prognosis and clinical management of this patient highlights the importance of recognizing unusual clinical presentations of more common, benign lesions within this patient population.

Morcos SM, Girardi M, Subtil A, Wilson LD, Cowper SE. Mycosis fungoides exhibiting features of a dermatofibroma: a case report and review of the literature.

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