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High Dose Intravenous IgG Reduces Platelet Associated Immunoglobulins and Complement in Idiopathic Thrombocytopenic Purpura
Article first published online: 24 APR 2009
DOI: 10.1111/j.1600-0609.1983.tb00662.x
© Munksgaard 1983
1600-0609/asset/cover.gif?v=1&s=946b5b431efb8410b6fa87b6a03da604c501f5f7 "Scandinavian Journal of Haematology")
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How to Cite
Winiarski, J., Kreuger, A., Ejderhamn, J. and Holm, G. (1983), High Dose Intravenous IgG Reduces Platelet Associated Immunoglobulins and Complement in Idiopathic Thrombocytopenic Purpura. Scandinavian Journal of Haematology, 31: 342–348. doi: 10.1111/j.1600-0609.1983.tb00662.x
Publication History
- Issue published online: 24 APR 2009
- Article first published online: 24 APR 2009
- Accepted for publication April 6, 1983
- Abstract
- References
- Cited By
Keywords:
- complement;
- idiopathic thrombocytopenic purpura;
- intravenous IgG;
- platelet antibodies
4 children with idiopathic thrombocytopenic purpura were treated with high dose i.v. IgG. Platelet associated immunoproteins were determined with an Elisa technique. Platelet counts increased in all patients, while simultaneously platelet associated IgG, IgA, IgM, C3 and C4 decreased. Serum antiplatelet antibody increased during treatment suggesting that administration of high doses of IgG interferes with the binding of antiplatelet antibody.