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Keywords:

  • human papillomavirus;
  • in situ hybridizaiton;
  • uterine cervix

Sixty different types of human papillomavirus (HPVs) have been isolated and characterized by molecular cloning in becteria (1). Animal models and pathological studies suggest an estiological role of HPV infection in the development and etiological role of HPV infection in the development of intraepithelial neoplasia and squamous cell carcinoma, particularly in the anogential tract, in the larynx and in edidermodysplasia verruciformis(2,3,4).