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Androgen receptor CAG repeat polymorphism in males of six non-human primate species

Authors


James N. Mubiru, Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Tel.: 210-258-9744
fax: 210-670-3323
e-mail: jmubiru@TxBiomed.org

Abstract

Background   Androgen receptor [CAG]n microsatellite has been linked to human diseases.

Methods  Six non-human primates were genotyped for the [CAG]n microsatellite.

Results  Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic.

Conclusions  Non-human primates that are polymorphic for the microsatellite are candidate animal models for CAG-related diseases.

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