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The Ultrastructure of Oral Neuromas in Multiple Mucosal Neuromas, Pheochromocytoma, Medullary Thyroid Carcinoma Syndrome
Article first published online: 28 APR 2006
DOI: 10.1111/j.1600-0714.1977.tb01647.x
1600-0714/asset/cover.gif?v=1&s=9df91ed0c5327d9f9770daeb9671206754a053f6 "Journal of Oral Pathology & Medicine")
Additional Information
How to Cite
Miller, R. L., Burzynski, N. J. and Giammara, B. L. (1977), The Ultrastructure of Oral Neuromas in Multiple Mucosal Neuromas, Pheochromocytoma, Medullary Thyroid Carcinoma Syndrome. Journal of Oral Pathology & Medicine, 6: 253–263. doi: 10.1111/j.1600-0714.1977.tb01647.x
Publication History
- Issue published online: 28 APR 2006
- Article first published online: 28 APR 2006
- Received 3 September, revised, accepted for publication 1 November 1976
- Abstract
- References
- Cited By
The ultrastructure of oral neuromas from 2 patients with multiple mucosal neuromas, pheochromocytoma, medullary thyroid carcinoma syndrome reveals numerous hypertrophic unmyelinated and myelinated axons, hyperplastic neurilemmal cells and associated collagen fiber formation. These tumors are described and compared ultrastructurally with neurilemomas and neurofibromas as described by other authors. On the basis of this comparison, these tumors are not considered to be of neurilemmal origin. On the basis of light and electron microscopic histology it is postulated that these tumors represent hypertrophy of axons similar to that noted in amputation neuromas.