Erythrodermic chronic actinic dermatitis responding only to topical tacrolimus


Dr. Roy A. Palmer
Department of Photobiology
Second Floor
St. John's Institute of Dermatology
South Wing Block 7
St. Thomas' Hospital
London SE1 7EH, UK
Tel: +44 207 928 9292 Ext 3066
Fax: +44 207 928 1621


Chronic actinic dermatitis (CAD) is a disorder characterized by an often severe persistent eczematous eruption induced by exposure to ultraviolet radiation. Treatment involves photoprotective measures and topical corticosteroid therapy and in more severe cases, systemic immunosuppression. Occasionally, however, the condition can prove very resistant to all therapy and be severely disabling. We report a patient with CAD who resisted standard topical and systemic treatments, but responded to topical tacrolimus ointment 0.1% (Protopic®).