Phototherapy: How does UV work?
Article first published online: 6 SEP 2005
Photodermatology, Photoimmunology & Photomedicine
Volume 21, Issue 5, pages 260–266, October 2005
How to Cite
Weichenthal, M. and Schwarz, T. (2005), Phototherapy: How does UV work?. Photodermatology, Photoimmunology & Photomedicine, 21: 260–266. doi: 10.1111/j.1600-0781.2005.00173.x
- Issue published online: 6 SEP 2005
- Article first published online: 6 SEP 2005
- Accepted for publication 31 May 2005
- mode of action;
Phototherapy has been largely empirical. Thus, despite the long term use its mechanisms of action are quite unclear. Because of the recent achievements in photoimmunology and molecular photobiology we are now beginning to understand some of the mechanisms. Many of the effects are certainly mediated via induction of apoptotic cell death. Another major mechanism is the induction of immunosuppression. This review primarily focuses on recent advances in photoimmunology which will contribute to the further understanding how phototherapy acts.