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Ultraviolet-B treatment for cutaneous lichen planus: our experience with 50 patients

Authors

  • Felix Pavlotsky,

    1. Department of Dermatology, Phototherapy and Day Care Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and
    2. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
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  • Nir Nathansohn,

    1. Department of Dermatology, Phototherapy and Day Care Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and
    2. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
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  • Grigory Kriger,

    1. Department of Dermatology, Phototherapy and Day Care Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and
    2. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
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  • Dorit Shpiro,

    1. Department of Dermatology, Phototherapy and Day Care Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and
    2. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
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  • Henri Trau

    1. Department of Dermatology, Phototherapy and Day Care Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and
    2. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
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  • Conflicts of interest:
    None declared.

Correspondence:
Felix Pavlotsky, M.D., Department of Dermatology, Phototherapy and Day Care Center, Chaim Sheba Medical Center, Tel Hashomer 52621, Ramat-Gan, Israel.
Tel: +972 3 530 2286
Fax: +972 3 530 4910
e-mail: felixp@post.tau.ac.il

Summary

Background: Previous small reports suggested the role of ultraviolet (UV)-B in the management of cutaneous lichen planus.

Objective: To summarize our experience with UVB in a relatively large study group looking specifically into predictive factors for complete response and the long-term relapse rates.

Methods: A retrospective analysis of 50 patients with generalized cutaneous lichen planus, treated by broad or narrow band UVB.

Results: Seven and 43 patients were treated by broad and narrow band UVB, respectively. Complete response was achieved in 70% and 85% of those were still in remission after a median of 34.7 months. The complete response rate and the need for higher cumulative exposure doses were not influenced by sex, age, skin type, presence of additional diseases, failure of previous treatment or disease duration.

Limitations: This is a retrospective non-randomized analysis of a usually self-limiting disease.

Conclusion: UVB is a safe and efficient treatment option for generalized cutaneous lichen planus.

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