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Narrowband UVB phototherapy as a novel treatment for Netherton syndrome


  • Conflicts of interest:

    None declared.


Sarah L. Stein, M.D., Section of Dermatology, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.

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Netherton syndrome (NS) is a rare congenital ichthyosis that is characterized by impaired skin barrier function. Topical medications are cautiously used in NS since toxicity from systemic absorption is a major concern. Narrowband ultraviolet B phototherapy is an alternative therapeutic option that demonstrated its beneficial and practical use in a patient with NS.