Evidence for a new paradigm for ultraviolet exposure: a universal schedule that is skin phototype independent

Authors


  • Conflicts of interest:

    None declared.

Correspondence:

Ms Sharon A. Miller, MSEE, Food and Drug Administration, Center for Devices and Radiological Health, 10903 New Hampshire Avenue, Bldg 62 Rm 1114, Silver Spring, MD 20993, USA.

Tel: +1 301 796 2471

Fax: +1 301 796 9927

e-mail: sharona.miller@fda.hhs.gov

Summary

Background

The Food and Drug Administration has published guidelines for manufacturer-recommended exposure schedules for ultraviolet (UV) tanning, intended to limit acute and delayed damage from UV exposure. These guidelines recommend that exposure schedules be adjusted for skin phototype. However, it has been shown that the dose necessary to produce tanning is similar for phototypes 2–4.

Methods

We observed tanning in phototypes 2 and 3 from repeated UV exposures over a 5-week period. Pigmentation was evaluated visually, instrumentally, and through Fontana-Masson staining of biopsies.

Results

The resultant pigmentation was equal or greater in phototype 3 compared with phototype 2 – both visually and instrumentally – measured on day 31 of the exposure protocol. The amount of melanin measured in biopsies taken 24 h postexposure was also greater in phototype 3 compared with phototype 2.

Conclusion

Published data on tanning in phototypes 4 and 5 support our findings that higher phototypes can develop pigmentation more efficiently than lower phototypes. Therefore, a universal exposure schedule (based on sensitivity of phototype 2) can be used for all phototypes that are expected to engage in indoor tanning. This approach will result in a reduction of the UV burden for skin phototypes 3 and above.

Ancillary