Exploratory laser flash photolysis study of free radical reactions and magnetic field effects in melatonin chemistry
Version of Record online: 30 JAN 2007
Journal of Pineal Research
Volume 19, Issue 4, pages 189–195, November 1995
How to Cite
Scaiano, J. C. (1995), Exploratory laser flash photolysis study of free radical reactions and magnetic field effects in melatonin chemistry. Journal of Pineal Research, 19: 189–195. doi: 10.1111/j.1600-079X.1995.tb00188.x
- Issue online: 30 JAN 2007
- Version of Record online: 30 JAN 2007
- Received August 7,1995; accepted September 26,1995.
- free radicals
Abstract: Melatonin is an excellent free radical scavenger, reacting with ferf-butoxyl and cumyloxyl radicals with rate constants of 3.4 × 107 and 6.7 × 107 M−1s−1, respectively. Reaction with benzophenone triplet occurs with a near-diffusion-controlled rate constant of 7.6 × 109 M−1s−1 in acetonitrile and probably involves charge transfer. When the radical pair formed by reaction of benzophenone triplet and melatonin is sequestered in a micelle, it is subject to extensive magnetic field effects that can be readily interpreted by the radical pair model.