The aging tendon


Professor Moira O'Brien, Department of Anatomy, University of Dublin, Trinity College, Dublin 2, Ireland


After maturation tendons undergo many biochemical, cellular, mechanical and pathological changes that bring about a general decline in the structure and function of the tendon. This decline in the aging tendon is characterized by a reduced ability to adapt to environmental stress and loss of tissue homeostasis. The tendon's adaptability to these changes will decide the rate and the success of treatment of a tendon injury. This review examines these changes and also looks at how we can curtail their progression through exercise and lifestyle modification.