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The objective evaluation of the severity of psoriatic scales with desquamation collecting tapes and image analysis

Authors

  • J. H. Kim,

    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Department of Dermatology, Seoul National University Bundang Hospital, Gyeonggi, Korea
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  • B. Y. Kim,

    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Department of Dermatology, Seoul National University Bundang Hospital, Gyeonggi, Korea
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  • J. W. Choi,

    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Department of Dermatology, Seoul National University Bundang Hospital, Gyeonggi, Korea
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  • S. O. Kim,

    1. Department of Dermatology, Seoul National University Bundang Hospital, Gyeonggi, Korea
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  • H. S. Lee,

    1. Department of Dermatology, Seoul National University Bundang Hospital, Gyeonggi, Korea
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  • K. C. Park,

    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Department of Dermatology, Seoul National University Bundang Hospital, Gyeonggi, Korea
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  • S. W. Youn

    1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    2. Department of Dermatology, Seoul National University Bundang Hospital, Gyeonggi, Korea
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Address:
Sang Woong Youn
Department of Dermatology
Seoul National University Bundang Hospital
166 Gumi-ro
Bundang-gu
Seongnam-si
Gyeonggi-do 463-707
Korea
Tel: +82 31 787 7312
Fax: +82 31 787 4058
e-mail: swyoun@snu.ac.kr

Abstract

Background: Assessment of psoriatic scales is important to determine the severity of psoriasis. However, there are very limited numbers of objective, quantitative and observer-independent tools for measuring the severity of psoriasis.

Objective: To determine whether the bioengineering parameters of the psoriatic scale can be used to assess the severity of psoriasis instead of the psoriatic severity index of scales (PSIs) score.

Methods: Thirty-four patients with psoriasis were included. A representative lesion from each patient was selected and bioengineering parameters were measured using the Corneofix®. Simultaneously, the severity of the scales was assessed by the PSIs score using clinical photographs of the lesions. In addition, skin color and elasticity parameters were also measured using the Colorimeter®, the Mexameter® and the Cutometer®.

Results: Statistical differences in the scale parameters were observed between the PSIs 2 and 3 scores. Among the scale parameters, the percent area and area in μm2 were negatively correlated with the PSIs score. In addition, the Colorimeter®a, b parameters and the Cutometer® R9 parameters were significantly correlated with the PSIs score.

Conclusions: The results of this study showed that the severity of psoriatic scales could be measured objectively using the Corneofix®.

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