A new methodology for evaluating the damage to the skin barrier caused by repeated application and removal of adhesive dressings
Article first published online: 13 JUN 2012
© 2012 John Wiley & Sons A/S
Skin Research and Technology
Volume 19, Issue 1, pages e366–e374, February 2013
How to Cite
Waring, M., Bielfeldt, S., Mätzold, K. and Wilhelm, K.-P. (2013), A new methodology for evaluating the damage to the skin barrier caused by repeated application and removal of adhesive dressings. Skin Research and Technology, 19: e366–e374. doi: 10.1111/j.1600-0846.2012.00653.x
- Issue published online: 7 JAN 2013
- Article first published online: 13 JUN 2012
- Manuscript Accepted: 26 APR 2012
- stratum corneum;
- barrier damage;
- adhesive dressings;
Chronic wounds require frequent dressing changes. Adhesive dressings used for this indication can be damaging to the stratum corneum, particularly in the elderly where the skin tends to be thinner. Understanding the level of damage caused by dressing removal can aid dressing selection.
This study used a novel methodology that applied a stain to the skin and measured the intensity of that stain after repeated application and removal of a series of different adhesive types. Additionally, a traditional method of measuring skin barrier damage (transepidermal water loss) was also undertaken and compared with the staining methodology.
The staining methodology and measurement of transepidermal water loss differentiated the adhesive dressings, showing that silicone adhesives caused least trauma to the skin.
The staining methodology was shown to be as effective as transepidermal water loss in detecting damage to the stratum corneum and was shown to detect disruption of the barrier earlier than the traditional technique.