Endoplasmic Reticulum Quality Control and the Unfolded Protein Response: Insights from Plants


  • Alessandro Vitale,

    Corresponding author
    1. Istituto di Biologia e Biotecnologia Agraria, Consiglio Nazionale delle Ricerche, via Bassini 15, 20133 Milano, Italy, EU
      *Alessandro Vitale, vitale@ibba.cnr.it
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  • Rebecca S. Boston

    Corresponding author
    1. Department of Plant Biology, North Carolina State University, Raleigh, NC 27695, USA
      Rebecca S. Boston, boston@unity.ncsu.edu
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*Alessandro Vitale, vitale@ibba.cnr.it and Rebecca S. Boston, boston@unity.ncsu.edu


Protein quality control (QC) within the endoplasmic reticulum and the related unfolded protein response (UPR) pathway of signal transduction are major regulators of the secretory pathway, which is involved in virtually any aspect of development and reproduction. The study of plant-specific processes such as pathogen response, seed development and the synthesis of seed storage proteins and of particular toxins is providing novel insights, with potential implications for the general recognition events and mechanisms of action of QC and UPR.