This work was supported in part by grant CA 23561 from the National Institutes of Health, by the Lymphoproliferative Research Fund, and by a Burroughs-Wellcome Travelling Grant.
Epstein-Barr Virus in Normal Pregnant Women*
Article first published online: 9 MAY 2013
American Journal of Reproductive Immunology
Volume 2, Issue 4, pages 217–221, August 1982
How to Cite
SAKAMOTO, K., GREALLY, J., GILFILLAN, R. F., SEXTON, J., BARNABEI, V., YETZ, J., BECHTOLD, T., SEELEY, J. K., O'DWYER, E. and PURTILO, D. T. (1982), Epstein-Barr Virus in Normal Pregnant Women. American Journal of Reproductive Immunology, 2: 217–221. doi: 10.1111/j.1600-0897.1982.tb00169.x
- Issue published online: 9 MAY 2013
- Article first published online: 9 MAY 2013
- Accepted May 15, 1982
- Epstein-Barr virus;
- immune suppression
ABSTRACT: Acquired immune suppression accompanying normal pregnancy may be associated with reactivation of Epstein-Barr virus (EBV). Pregnant women with reactivated EBV having anti-EA antibodies show high titers of antiviral capsid antigen (VCA) geometric mean titers (GMT) of 522 versus 170 in those lacking anti-early antigen (EA). Among twenty-seven seropositive women at parturition, 17 (63%) had generated antibody to EA, and all 27 (100%) demonstrated significant increases in antibody to VCA (p < 0.01). In contrast, antibody titers to cytomegalovirus, herpes hominis, varicella-zoster, and rubella viruses in the pregnant women were comparable to those found in nonpregnant controls.