This work was supported by a grant from the Medical Research Council of Canada and the National Cancer Institute of Canada.
Life History of Decidual Cells: A Review*
Article first published online: 9 MAY 2013
American Journal of Reproductive Immunology
Volume 3, Issue 2, pages 78–82, March 1983
How to Cite
KEARNS, M. and LALA, P. K. (1983), Life History of Decidual Cells: A Review. American Journal of Reproductive Immunology, 3: 78–82. doi: 10.1111/j.1600-0897.1983.tb00219.x
- Issue published online: 9 MAY 2013
- Article first published online: 9 MAY 2013
- Accepted July 28, 1982
- Decidual cells;
- bone marrow chimeras
ABSTRACT: Decidual cells are a distinctive cell population observed in the mammalian endometrium during pregnancy. Their appearance can also be induced with appropriate stimuli in the hormone-primed pseudopregnant uterus. This review deals with their life history, including the dynamic morphological events during the process of decidualization, cytochemical markers for decidual cell reaction, the surface markers and functions of decidual cells, and, finally, the origin and fate of this cell class. The recent discovery of the bone marrow origin of decidual cell precursors adds a new dimension to decidual cell biology. Future studies of steps in the differentiation of the decidual cell lineage await the identification of unique lineage-specific cell-surface or cytoplasmic marker(s); a precise knowledge of decidual cell functions can only be obtained from a discriminating analysis using purified cell populations.