Effects of Serum from Pregnant Versus Nonpregnant Women on Natural Killer Cell Activity
Article first published online: 6 SEP 2011
American Journal of Reproductive Immunology
Volume 37, Issue 5, pages 365–367, May 1997
How to Cite
Fujino, Y., Nakamura, Y., Ueda, K., Ozaki, K., Ito, F., Sun, T.-T., Umesaki, N. and Ogita, S. (1997), Effects of Serum from Pregnant Versus Nonpregnant Women on Natural Killer Cell Activity. American Journal of Reproductive Immunology, 37: 365–367. doi: 10.1111/j.1600-0897.1997.tb00245.x
- Issue published online: 6 SEP 2011
- Article first published online: 6 SEP 2011
- Accepted January 13, 1997
- In vitro fertilization and embryo transfer;
- NK cell;
- serum effect
PROBLEM: To test the effect of serum obtained from in vitro fertilization-embryo transfer (IVF-ET) patients on the healthy volunteers natural killer (NK) cell activity.
METHOD OF STUDY: Retrospective non-randomized clinical study. Suppressive effect on NK cell activity was measured with serum obtained from 25 pregnant and 24 non-pregnant women during IVF-ET procedure.
RESULTS: Suppressive serum effect of volunteers' NK cell activity was significantly higher in pregnant than in non-pregnant women (P < 0.01).
CONCLUSIONS: The suppressive activity of serum from pregnant women on NK cell suppression activity was useful in predicting the establishment of a successful pregnancy.