SEARCH

SEARCH BY CITATION

References

  • 1
    Sharlip ID, Jarow JP, Belker AM, Lipshultz LI, Sigman M, Thomas AJ, Schlegel PN, Howards SS, Nehra A, Damewood MD, Overstreet JW, Sadovsky R: Best practice policies for male infertility. Fertil Steril 2002; 77:873882.
  • 2
    Sies H: Strategies of antioxidant defense. Eur J Biochem 1993; 215:213219.
  • 3
    De Lamirande E, Gagnon C: Impact of reactive oxygen species on spermatozoa: a balancing act between beneficial and detrimental effects. Hum Reprod 1995; 10(Suppl. 1):1521.
  • 4
    Agarwal A, Prabakaran SA: Mechanism, measurement, and prevention of oxidative stress in male reproductive physiology. Indian J Exp Biol 2005; 43:963974.
  • 5
    Aitken RJ: Molecular mechanisms regulating human sperm function. Mol Hum Reprod 1997; 3:169173.
  • 6
    Aitken RJ: The Amoroso Lecture. The human spermatozoon–a cell in crisis?. J Reprod Fertil 1999; 115:17.
  • 7
    Gagnon C, Iwasaki A, De Lamirande E, Kovalski N: Reactive oxygen species and human spermatozoa. Ann N Y Acad Sci 1991; 637:436444.
  • 8
    Agarwal A, Nallella KP, Allamaneni SS, Said TM: Role of antioxidants in treatment of male infertility: an overview of the literature. Reprod Biomed Online 2004; 8:616627.
  • 9
    Griveau JF, Le Lannou D: Reactive oxygen species and human spermatozoa: physiology and pathology. Int J Androl 1997; 20:6169.
  • 10
    De Lamirande E, Eiley D, Gagnon C: Inverse relationship between the induction of human sperm capacitation and spontaneous acrosome reaction by various biological fluids and the superoxide scavenging capacity of these fluids. Int J Androl 1993; 16:258266.
  • 11
    Griveau JF, Renard P, Le Lannou D: An in vitro promoting role for hydrogen peroxide in human sperm capacitation. Int J Androl 1994; 17:300307.
  • 12
    Aitken RJ: Free radicals, lipid peroxidation and sperm function. Reprod Fertil Dev 1995; 7:659668.
  • 13
    Kodama H, Kuribayashi Y, Gagnon C: Effect of sperm lipid peroxidation on fertilization. J Androl 1996; 17:151157.
  • 14
    Griveau JF, Dumont E, Renard P, Callegari JP, Le Lannou D: Reactive oxygen species, lipid peroxidation and enzymatic defence systems in human spermatozoa. J Reprod Fertil 1995; 103:1726.
  • 15
    Agarwal A, Prabhakaran SA, Sikka SC: Clinical relevance of oxidative stress in patients with male factor infertility: evidence-based analysis. AUA Update Series 2007; 26:112.
  • 16
    Sikka SC: Relative impact of oxidative stress on male reproductive function. Curr Med Chem 2001; 8:851862.
  • 17
    Darley-Usmar V, Wiseman H, Halliwell B: Nitric oxide and oxygen radicals: a question of balance. FEBS Lett 1995; 369:131135.
  • 18
    Wu TP, Huang BM, Tsai HC, Lui MC, Liu MY: Effects of nitric oxide on human spermatozoa activity, fertilization and mouse embryonic development. Arch Androl 2004; 50:173179.
  • 19
    Garrido N, Meseguer M, Simon C, Pellicer A, Remohi J: Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility. Asian J Androl 2004; 6:5965.
  • 20
    Gomez E, Buckingham DW, Brindle J, Lanzafame F, Irvine DS, Aitken RJ: Development of an image analysis system to monitor the retention of residual cytoplasm by human spermatozoa: correlation with biochemical markers of the cytoplasmic space, oxidative stress, and sperm function. J Androl 1996; 17:276287.
  • 21
    Aitken RJ, Buckingham DW, West KM: Reactive oxygen species and human spermatozoa: analysis of the cellular mechanisms involved in luminol- and lucigenin-dependent chemiluminescence. J Cell Physiol 1992; 151:466477.
  • 22
    Gavella M, Lipovac V: NADH-dependent oxidoreductase (diaphorase) activity and isozyme pattern of sperm in infertile men. Arch Androl 1992; 28:135141.
  • 23
    Thomas J, Fishel SB, Hall JA, Green S, Newton TA, Thornton SJ: Increased polymorphonuclear granulocytes in seminal plasma in relation to sperm morphology. Hum Reprod 1997; 12:24182421.
  • 24
    Wolff H: The biologic significance of white blood cells in semen. Fertil Steril 1995; 63:11431157.
  • 25
    Tomlinson MJ, Barratt CL, Cooke ID: Prospective study of leukocytes and leukocyte subpopulations in semen suggests they are not a cause of male infertility. Fertil Steril 1993; 60:10691075.
  • 26
    Aitken J, Krausz C, Buckingham D: Relationships between biochemical markers for residual sperm cytoplasm, reactive oxygen species generation, and the presence of leukocytes and precursor germ cells in human sperm suspensions. Mol Reprod Dev 1994; 39:268279.
  • 27
    Athayde KS, Cocuzza M, Agarwal A, Krajcir N, Lucon AM, Srougi M, Hallak J: Development of normal reference values for seminal reactive oxygen species and their correlation with leukocytes and semen parameters in a fertile population. J Androl 2007; 28:613620.
  • 28
    Sharma RK, Pasqualotto AE, Nelson DR, Thomas AJ Jr, Agarwal A: Relationship between seminal white blood cell counts and oxidative stress in men treated at an infertility clinic. J Androl 2001; 22:575583.
  • 29
    Pasqualotto FF, Sharma RK, Potts JM, Nelson DR, Thomas AJ, Agarwal A: Seminal oxidative stress in patients with chronic prostatitis. Urology 2000; 55:881885.
  • 30
    Plante M, De Lamirande E, Gagnon C: Reactive oxygen species released by activated neutrophils, but not by deficient spermatozoa, are sufficient to affect normal sperm motility. Fertil Steril 1994; 62:387393.
  • 31
    Shekarriz M, Sharma RK, Thomas AJ Jr, Agarwal A: Positive myeloperoxidase staining (Endtz test) as an indicator of excessive reactive oxygen species formation in semen. J Assist Reprod Genet 1995; 12:7074.
  • 32
    Aitken RJ, Clarkson JS, Fishel S: Generation of reactive oxygen species, lipid peroxidation, and human sperm function. Biol Reprod 1989; 41:183197.
  • 33
    Aitken RJ, Harkiss D, Buckingham DW: Analysis of lipid peroxidation mechanisms in human spermatozoa. Mol Reprod Dev 1993; 35:302315.
  • 34
    Aitken RJ, Wingate JK, De Iuliis GN, McLaughlin EA: Analysis of lipid peroxidation in human spermatozoa using BODIPY C11. Mol Hum Reprod 2007; 13:203211.
  • 35
    Lenzi A, Lombardo F, Gandini L, Alfano P, Dondero F: Computer assisted sperm motility analysis at the moment of induced pregnancy during gonadotropin treatment for hypogonadotropic hypogonadism. J Endocrinol Invest 1993; 16:683686.
  • 36
    Agarwal A, Ikemoto I, Loughlin KR: Relationship of sperm parameters with levels of reactive oxygen species in semen specimens. J Urol 1994; 152:107110.
  • 37
    Armstrong JS, Rajasekaran M, Chamulitrat W, Gatti P, Hellstrom WJ, Sikka SC: Characterization of reactive oxygen species induced effects on human spermatozoa movement and energy metabolism. Free Radic Biol Med 1999; 26:869880.
  • 38
    Aitken RJ, Fisher HM, Fulton N, Gomez E, Knox W, Lewis B, Irvine S: Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine. Mol Reprod Dev 1997; 47:468482.
  • 39
    De Lamirande E, Gagnon C: Reactive oxygen species and human spermatozoa. II. Depletion of adenosine triphosphate plays an important role in the inhibition of sperm motility. J Androl 1992; 13:379386.
  • 40
    Gomez E, Irvine DS, Aitken RJ: Evaluation of a spectrophotometric assay for the measurement of malondialdehyde and 4-hydroxyalkenals in human spermatozoa: relationships with semen quality and sperm function. Int J Androl 1998; 21:8194.
  • 41
    Suleiman SA, Ali ME, Zaki ZM, El-Malik EM, Nasr MA: Lipid peroxidation and human sperm motility: protective role of vitamin E. J Androl 1996; 17:530537.
  • 42
    Kodama H, Yamaguchi R, Fukuda J, Kasai H, Tanaka T: Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients. Fertil Steril 1997; 68:519524.
  • 43
    Barroso G, Morshedi M, Oehninger S: Analysis of DNA fragmentation, plasma membrane translocation of phosphatidylserine and oxidative stress in human spermatozoa. Hum Reprod 2000; 15:13381344.
  • 44
    Kemal Duru N, Morshedi M, Oehninger S: Effects of hydrogen peroxide on DNA and plasma membrane integrity of human spermatozoa. Fertil Steril 2000; 74:12001207.
  • 45
    Aitken RJ, Krausz C: Oxidative stress, DNA damage and the Y chromosome. Reproduction 2001; 122:497506.
  • 46
    Spiropoulos J, Turnbull DM, Chinnery PF: Can mitochondrial DNA mutations cause sperm dysfunction? Mol Hum Reprod 2002; 8:719721.
  • 47
    Sharma RK, Said T, Agarwal A: Sperm DNA damage and its clinical relevance in assessing reproductive outcome. Asian J Androl 2004; 6:139148.
  • 48
    Sakkas D, Mariethoz E, Manicardi G, Bizzaro D, Bianchi PG, Bianchi U: Origin of DNA damage in ejaculated human spermatozoa. Rev Reprod 1999; 4:3137.
  • 49
    Lee J, Richburg JH, Younkin SC, Boekelheide K: The Fas system is a key regulator of germ cell apoptosis in the testis. Endocrinology 1997; 138:20812088.
  • 50
    Wang X, Sharma RK, Sikka SC, Thomas AJ Jr, Falcone T, Agarwal A: Oxidative stress is associated with increased apoptosis leading to spermatozoa DNA damage in patients with male factor infertility. Fertil Steril 2003; 80:531535.
  • 51
    Agarwal A, Saleh RA, Bedaiwy MA: Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil Steril 2003; 79:829843.
  • 52
    Gonda RL Jr, Karo JJ, Forte RA, O’Donnell KT: Diagnosis of subclinical varicocele in infertility. AJR Am J Roentgenol 1987; 148:7175.
  • 53
    Schoor RA, Elhanbly SM, Niederberger C: The pathophysiology of varicocele-associated male infertility. Curr Urol Rep 2001; 2:432436.
  • 54
    Koksal IT, Usta M, Orhan I, Abbasoglu S, Kadioglu A: Potential role of reactive oxygen species on testicular pathology associated with infertility. Asian J Androl 2003; 5:9599.
  • 55
    Mitropoulos D, Deliconstantinos G, Zervas A, Villiotou V, Dimopoulos C, Stavrides J: Nitric oxide synthase and xanthine oxidase activities in the spermatic vein of patients with varicocele: a potential role for nitric oxide and peroxynitrite in sperm dysfunction. J Urol 1996; 156:19521958.
  • 56
    Romeo C, Ientile R, Santoro G, Impellizzeri P, Turiaco N, Impala P, Cifala S, Cutroneo G, Trimarchi F, Gentile C: Nitric oxide production is increased in the spermatic veins of adolescents with left idiophatic varicocele. J Pediatr Surg 2001; 36:389393.
  • 57
    Ozbek E, Turkoz Y, Gokdeniz R, Davarci M, Ozugurlu F: Increased nitric oxide production in the spermatic vein of patients with varicocele. Eur Urol 2000; 37:172175.
  • 58
    Mostafa T, Anis TH, El-Nashar A, Imam H, Othman IA: Varicocelectomy reduces reactive oxygen species levels and increases antioxidant activity of seminal plasma from infertile men with varicocele. Int J Androl 2001; 24:261265.
  • 59
    Allamaneni SS, Naughton CK, Sharma RK, Thomas AJ Jr, Agarwal A: Increased seminal reactive oxygen species levels in patients with varicoceles correlate with varicocele grade but not with testis size. Fertil Steril 2004; 82:16841686.
  • 60
    Agarwal A, Prabakaran S, Allamaneni SS: Relationship between oxidative stress, varicocele and infertility: a meta-analysis. Reprod Biomed Online 2006; 12:630633.
  • 61
    Aitken RJ, Koopman P, Lewis SE: Seeds of concern. Nature 2004; 432:4852.
  • 62
    Sun JG, Jurisicova A, Casper RF: Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol Reprod 1997; 56:602607.
  • 63
    Zavos PM, Correa JR, Karagounis CS, Ahparaki A, Phoroglou C, Hicks CL, Zarmakoupis-Zavos PN: An electron microscope study of the axonemal ultrastructure in human spermatozoa from male smokers and nonsmokers. Fertil Steril 1998; 69:430434.
  • 64
    Vine MF, Tse CK, Hu P, Truong KY: Cigarette smoking and semen quality. Fertil Steril 1996; 65:835842.
  • 65
    Potts RJ, Newbury CJ, Smith G, Notarianni LJ, Jefferies TM: Sperm chromatin damage associated with male smoking. Mutat Res 1999; 423:103111.
  • 66
    Kunzle R, Mueller MD, Hanggi W, Birkhauser MH, Drescher H, Bersinger NA: Semen quality of male smokers and nonsmokers in infertile couples. Fertil Steril 2003; 79:287291.
  • 67
    Aitken RJ, Baker MA, O’Bryan M: Shedding light on chemiluminescence: the application of chemiluminescence in diagnostic andrology. J Androl 2004; 25:455465.
  • 68
    Hull MG, North K, Taylor H, Farrow A, Ford WC: Delayed conception and active and passive smoking. The Avon Longitudinal Study of Pregnancy and Childhood Study Team. Fertil Steril 2000; 74:725733.
  • 69
    Frei B, Kim MC, Ames BN: Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations. Proc Natl Acad Sci U S A 1990; 87:48794883.
  • 70
    Lewin A, Lavon H: The effect of coenzyme Q10 on sperm motility and function. Mol Aspects Med 1997; 18(Suppl.):S213219.
  • 71
    Karbownik M, Gitto E, Lewinski A, Reiter RJ: Induction of lipid peroxidation in hamster organs by the carcinogen cadmium: melioration by melatonin. Cell Biol Toxicol 2001; 17:3340.
  • 72
    Lenzi A, Sgro P, Salacone P, Paoli D, Gilio B, Lombardo F, Santulli M, Agarwal A, Gandini L: A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia. Fertil Steril 2004; 81:15781584.
  • 73
    Meseguer M, Garrido N, Martinez-Conejero JA, Simon C, Pellicer A, Remohi J: Role of cholesterol, calcium, and mitochondrial activity in the susceptibility for cryodamage after a cycle of freezing and thawing. Fertil Steril 2004; 81:588594.
  • 74
    Park NC, Park HJ, Lee KM, Shin DG: Free radical scavenger effect of rebamipide in sperm processing and cryopreservation. Asian J Androl 2003; 5:195201.
  • 75
    Askari HA, Check JH, Peymer N, Bollendorf A: Effect of natural antioxidants tocopherol and ascorbic acids in maintenance of sperm activity during freeze-thaw process. Arch Androl 1994; 33:1115.
  • 76
    Greco E, Iacobelli M, Rienzi L, Ubaldi F, Ferrero S, Tesarik J: Reduction of the incidence of sperm DNA fragmentation by oral antioxidant treatment. J Androl 2005; 26:349353.
  • 77
    Greco E, Romano S, Iacobelli M, Ferrero S, Baroni E, Minasi MG, Ubaldi F, Rienzi L, Tesarik J: ICSI in cases of sperm DNA damage: beneficial effect of oral antioxidant treatment. Hum Reprod 2005; 20:25902594.
  • 78
    Hughes CM, Lewis SE, McKelvey-Martin VJ, Thompson W: The effects of antioxidant supplementation during Percoll preparation on human sperm DNA integrity. Hum Reprod 1998; 13:12401247.
  • 79
    Twigg J, Irvine DS, Houston P, Fulton N, Michael L, Aitken RJ: Iatrogenic DNA damage induced in human spermatozoa during sperm preparation: protective significance of seminal plasma. Mol Hum Reprod 1998; 4:439445.
  • 80
    Twigg JP, Irvine DS, Aitken RJ: Oxidative damage to DNA in human spermatozoa does not preclude pronucleus formation at intracytoplasmic sperm injection. Hum Reprod 1998; 13:18641871.
  • 81
    Bedaiwy MA, Falcone T, Mohamed MS, Aleem AA, Sharma RK, Worley SE, Thornton J, Agarwal A: Differential growth of human embryos in vitro: role of reactive oxygen species. Fertil Steril 2004; 82:593600.
  • 82
    Sikka SC: Role of oxidative stress and antioxidants in andrology and assisted reproductive technology. J Androl 2004; 25:518.
  • 83
    Zhang X, Sharma RK, Agarwal A, Falcone T: Effect of pentoxifylline in reducing oxidative stress-induced embryotoxicity. J Assist Reprod Genet 2005; 22:415417.
  • 84
    Esfandiari N, Falcone T, Agarwal A, Attaran M, Nelson DR, Sharma RK: Protein supplementation and the incidence of apoptosis and oxidative stress in mouse embryos. Obstet Gynecol 2005; 105:653660.
  • 85
    Tatemoto H, Ootaki K, Shigeta K, Muto N: Enhancement of developmental competence after in vitro fertilization of porcine oocytes by treatment with ascorbic acid 2-O-alpha-glucoside during in vitro maturation. Biol Reprod 2001; 65:18001806.
  • 86
    Ali AA, Bilodeau JF, Sirard MA: Antioxidant requirements for bovine oocytes varies during in vitro maturation, fertilization and development. Theriogenology 2003; 59:939949.
  • 87
    Guerin P, Guillaud J, Menezo Y: Hypotaurine in spermatozoa and genital secretions and its production by oviduct epithelial cells in vitro. Hum Reprod 1995; 10:866872.
  • 88
    Aitken RJ, Harkiss D, Buckingham D: Relationship between iron-catalysed lipid peroxidation potential and human sperm function. J Reprod Fertil 1993; 98:257265.
  • 89
    Aitken RJ, Gordon E, Harkiss D, Twigg JP, Milne P, Jennings Z, Irvine DS: Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa. Biol Reprod 1998; 59:10371046.
  • 90
    Wroblewski N, Schill WB, Henkel R: Metal chelators change the human sperm motility pattern. Fertil Steril 2003; 79(Suppl. 3):15841589.
  • 91
    Aziz N, Said T, Paasch U, Agarwal A: The relationship between human sperm apoptosis, morphology and the sperm deformity index. Hum Reprod 2007; 22:14131419.
  • 92
    Grunewald S, Paasch U, Glander HJ: Enrichment of non-apoptotic human spermatozoa after cryopreservation by immunomagnetic cell sorting. Cell Tissue Bank 2001; 2:127133.
  • 93
    Grunewald S, Paasch U, Said TM, Rasch M, Agarwal A, Glander HJ: Magnetic-activated cell sorting before cryopreservation preserves mitochondrial integrity in human spermatozoa. Cell Tissue Bank 2006; 7:99104.
  • 94
    Said TM, Grunewald S, Paasch U, Rasch M, Agarwal A, Glander HJ: Effects of magnetic-activated cell sorting on sperm motility and cryosurvival rates. Fertil Steril 2005; 83:14421446.
  • 95
    Said TM, Grunewald S, Paasch U, Glander HJ, Baumann T, Kriegel C, Li L, Agarwal A: Advantage of combining magnetic cell separation with sperm preparation techniques. Reprod Biomed Online 2005; 10:740746.
  • 96
    Said TM, Agarwal A, Grunewald S, Rasch M, Glander HJ, Paasch U: Evaluation of sperm recovery following annexin V magnetic-activated cell sorting separation. Reprod Biomed Online 2006; 13:336339.
  • 97
    Said T, Agarwal A, Grunewald S, Rasch M, Baumann T, Kriegel C, Li L, Glander HJ, Thomas AJ Jr, Paasch U: Selection of nonapoptotic spermatozoa as a new tool for enhancing assisted reproduction outcomes: an in vitro model. Biol Reprod 2006; 74:530537.