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First Successful Pregnancy after Addition of Enoxaparin to Sildenafil and Etanercept Immunotherapy in Woman with Fifteen Failed IVF Cycles – Case Report


  • This work was supported by grant nr N N407 246634 from Ministry of Science and Higher Education, Poland.

Corresponding Małgorzata Jerzak, Department of Gynecology and Gynecological Oncology, Military Institute of Health Services, 128 Szaserów str., 00-909 Warsaw, Poland.


Citation Jerzak M, Niemiec T, Nowakowska A, Klochowicz M, Górski A, Baranowski W. First successful pregnancy after addition of enoxaparin to sildenafil and etanercept immunotherapy in woman with fifteen failed in vitro fertilization (IVF) cycles – case report. Am J Reprod Immunol 2010; 64: 93–96

Problem  Does addition of enoxaparin to sildenafil and etanercept immunotherapy improve IVF outcome?

Methods  Report of a striking case with 15 IVF failures.

Result  When enoxaparin was added, the 16th IVF cycle generated a healthy male baby.

Conclusions  Combination therapy that includes a heparin may allow successful IVF outcome and this issue merits further study.

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