Resistin Concentration is Increased in the Peritoneal Fluid of Women with Endometriosis
Article first published online: 30 APR 2010
© 2010 John Wiley & Sons A/S
American Journal of Reproductive Immunology
Volume 64, Issue 5, pages 318–323, November 2010
How to Cite
Yi, K. W., Shin, J.-H., Park, H. T., Kim, T., Kim, S. H. and Hur, J.-Y. (2010), Resistin Concentration is Increased in the Peritoneal Fluid of Women with Endometriosis. American Journal of Reproductive Immunology, 64: 318–323. doi: 10.1111/j.1600-0897.2010.00840.x
- Issue published online: 30 APR 2010
- Article first published online: 30 APR 2010
- Submitted December17, 2009; accepted February 16, 2010.
- peritoneal fluid;
Citation Yi KW, Shin J-H, Park HT, Kim T, Kim SH, Hur J-Y. Resistin concentration is increased in the peritoneal fluid of women with endometriosis. Am J Reprod Immunol 2010
Problem The aim of this study was to investigate the concentration of resistin and adiponectin in the peritoneal fluid (PF) of patients with endometriosis.
Method of study PF sampling was obtained from women with (n = 48) and without endometriosis (n = 36), and the anthropometric indices of the patients were measured. Resistin and adiponectin concentrations in the PF were determined using the enzyme-linked immunosorbent assay.
Results The mean concentration of PF resistin was significantly higher in women with endometriosis compared to the controls. PF resistin concentrations were not associated with any of the anthropometric indices. The PF adiponectin did not differ between the two groups, but showed a significant association with the weight, body mass index, and hip circumference. After adjusting for these factors, PF adiponectin expression was not associated with endometriosis.
Conclusion The findings of this study suggest a potent role for resistin in endometriosis. Further studies are needed to elucidate the biological implications of resistin in endometriosis.