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Resistin Concentration is Increased in the Peritoneal Fluid of Women with Endometriosis


Jung-Ho Shin, Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, 80, Guro-dong, Guro-gu, Seoul 152-703, Korea.


Citation Yi KW, Shin J-H, Park HT, Kim T, Kim SH, Hur J-Y. Resistin concentration is increased in the peritoneal fluid of women with endometriosis. Am J Reprod Immunol 2010

Problem  The aim of this study was to investigate the concentration of resistin and adiponectin in the peritoneal fluid (PF) of patients with endometriosis.

Method of study  PF sampling was obtained from women with (n = 48) and without endometriosis (n = 36), and the anthropometric indices of the patients were measured. Resistin and adiponectin concentrations in the PF were determined using the enzyme-linked immunosorbent assay.

Results  The mean concentration of PF resistin was significantly higher in women with endometriosis compared to the controls. PF resistin concentrations were not associated with any of the anthropometric indices. The PF adiponectin did not differ between the two groups, but showed a significant association with the weight, body mass index, and hip circumference. After adjusting for these factors, PF adiponectin expression was not associated with endometriosis.

Conclusion  The findings of this study suggest a potent role for resistin in endometriosis. Further studies are needed to elucidate the biological implications of resistin in endometriosis.

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