• 1
    Fukumori T, Ohkohchi N, Tsukamoto S, Satomi S. Why is fatty liver unsuitable for transplantation? Deterioration of mitochondrial ATP synthesis and sinusoidal structure during cold preservation of a liver with steatosis. Transplant Proc 1997; 29: 412415.
  • 2
    Marcos A, Ham JM, Fisher RA, Olzinski AT, Posner MP. Single-center analysis of the first 40 adult-to-adult living donor liver transplants using the right lobe. Liver Transpl 2000; 6: 296301.
  • 3
    Akabayashi A, Slingsby BT, Fujita M. The first donor death after living-related liver transplantation in Japan. Transplantation 2004; 77: 634.
  • 4
    Sun CK, Zhang XY, Zimmermann A, Davis G, Wheatley AM. Effect of ischemia-reperfusion injury on the microcirculation of the steatotic liver of the Zucker rat. Transplantation 2001; 72: 16251631.
  • 5
    Man K, Lo CM, Ng IO et al. Liver transplantation in rats using small-for-size grafts: A study of hemodynamic and morphological changes. Arch Surg 2001; 136: 280285.
  • 6
    Man K, Lo CM, Lee TK, Li XL, Ng IO, Fan ST. Intragraft gene expression profiles by cDNA microarray in small-for-size liver grafts. Liver Transpl 2003; 9: 425432.
  • 7
    Man K, Fan ST, Lo CM et al. Graft injury in relation to graft size in right lobe live donor liver transplantation: A study of hepatic sinusoidal injury in correlation with portal hemodynamics and intragraft gene expression. Ann Surg 2003; 237: 256264.
  • 8
    Amersi F, Farmer DG, Shaw GD et al. P-selectin glycoprotein ligand-1 (rPSGL-Ig)-mediated blockade of CD62 selectin molecules protects rat steatotic liver grafts from ischemia/reperfusion injury. Am J Transplant 2002; 2: 600608.
  • 9
    Coito AJ, Buelow R, Shen XD et al. Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia-reperfusion injury. Transplantation 2002; 74: 96102.
  • 10
    Mokuno Y, Berthiaume F, Tompkins RG, Balis UJ, Yarmush ML. Technique for expanding the donor liver pool: Heat shock preconditioning in a rat fatty liver model. Liver Transpl 2004; 10: 264272.
  • 11
    Selzner N, Selzner M, Jochum W, Clavien PA. Ischemic preconditioning protects the steatotic mouse liver against reperfusion injury: An ATP dependent mechanism. J Hepatol 2003; 39: 5561.
  • 12
    Todo S, Demetris AJ, Makowka L et al. Primary nonfunction of hepatic allografts with preexisting fatty infiltration. Transplantation 1989; 47: 903905.
  • 13
    Chui AK, Shi LW, Rao AR et al. Donor fatty (steatotic) liver allografts in orthotopic liver transplantation: A revisit. Transplant Proc 2000; 32: 21012102.
  • 14
    Yamauchi T, Kamon J, Waki H et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2000; 7: 941946.
  • 15
    Berg AH, Combs TP, Scherer PE. ACRP30/adiponectin: An adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 2002; 13: 8489.
  • 16
    Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003; 112: 91100.
  • 17
    Masaki T, Chiba S, Tatsukawa H et al. Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice. Hepatology 2004; 40: 177184.
  • 18
    Zhao Y, Man K, Lo CM et al. Attenuation of small-for-size liver graft injury by FTY720: Significance of cell-survival Akt signaling pathway. Am J Transplant 2004; 4: 13991407.
  • 19
    Fraser JL, Antonioli DA, Chopra S, Wang HH. Prevalence and nonspecificity of microvesicular fatty change in the liver. Mod Pathol 1995; 8: 6570.
  • 20
    Xu A, Yin S, Wong L, Chan KW, Lam KS. Adiponectin ameliorates dyslipidemia induced by the human immunodeficiency virus protease inhibitor ritonavir in mice. Endocrinology 2004; 145: 487494.
  • 21
    Uehara Y, Urata H, Ideishi M, Arakawa K, Saku K. Chymase inhibition suppresses high-cholesterol diet-induced lipid accumulation in the hamster aorta. Cardiovasc Res 2002; 55: 870876.
  • 22
    Liang TB, Man K, Kin-Wah Lee T et al. Distinct intragraft response pattern in relation to graft size in liver transplantation. Transplantation 2003; 75: 673678.
  • 23
    Wang Y, Lu G, Wong WP et al. Proteomic and functional characterization of endogenous adiponectin purified from fetal bovine serum. Proteomics 2004; 4: 39333942.
  • 24
    Cortez-Pinto H, Zhi Lin H, Qi Yang S, Odwin Da Costa S, Diehl AM. Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes. Gastroenterology 1999; 116: 11841193.
  • 25
    Yang S, Zhu H, Li Y et al. Mitochondrial adaptations to obesity-related oxidant stress. Arch Biochem Biophys 2000; 378: 259268.
  • 26
    Chavin KD, Fiorini RN, Shafizadeh S et al. Fatty acid synthase blockade protects steatotic livers from warm ischemia reperfusion injury and transplantation. Am J Transplant 2004; 4: 14401447.
  • 27
    Chen H, Montagnani M, Funahashi T, Shimomura I, Quon MJ. Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem 2003; 278: 4502145026.
  • 28
    Man K, Lee TK, Liang TB et al. FK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway. Ann Surg 2004; 240: 159168.
  • 29
    Haga S, Ogawa W, Inoue H et al. Compensatory recovery of liver mass by Akt-mediated hepatocellular hypertrophy in liver-specific STAT3-deficient mice. J Hepatol 2005; [E-pub ahead of print.