We reviewed all abstracts (n = 1178) included in the Scientific Program of Abstracts (11) for Transplant 2000, the First Joint Annual Meeting of American Society of Transplant Surgeons and the American Society of Transplantation held May 13–17, 2000, in Chicago, Illinois.
For each abstract, data from the following predetermined domains were identified: name of first and senior author, department and country of origin at the time of abstract submission. Abstract qualification included presentation type (oral vs. poster), research type [clinical (involving intact human subjects) vs. basic science], study methodology as defined by traditional epidemiological definitions (12) (randomized controlled trial, cohort study, case-control study, case series or other), organ type, human or non-human study subjects, sample size, reported statistical significance of primary outcome, collaborative group studies and single center versus multi-centered. The later included research studies with two or more independent research sites. When more than one country was listed, the country of the first author was considered the country of origin for the abstract. For the purposes of analysis, organ type was categorized as liver, heart, kidney and other (lung, pancreas, islet, multi-organ, small bowel, cells or skin, hematopoetic, retina). Industry sponsorship was considered present if a pharmaceutical company was listed within the abstract as a sponsor. We did not use the disclosure index included in the program of abstracts to determine industry sponsorship since the specific industry relation was not identified (i.e. disclosure could have been for several reasons such as study sponsorship, speakers fees, advisory board etc.). Primary data abstraction was carried out by three investigators. Validation of abstracted data was carried out by another investigator who randomly selected abstracts for review. Differences were resolved by consensus.
To determine full publication status, an English database search of Medline, PubMed and EMBASE was conducted. The first, second and final author, as well as abstract keywords were searched individually and as combined (AND) search terms. The identified publications were reviewed as per their objectives, methodology and results, to confirm the publication resulted directly from the research described in the corresponding abstract. Time to publication was the difference in days, between the date of publication (rounded to the first day of the month) and date of abstract presentation. The final date for the publication search was November 1, 2004.