• 1
    Stevenson LW, Sietsema K, Tillisch JH et al. Exercise capacity for survivors of cardiac transplantation or sustained medical therapy for stable heart failure. Circulation 1990; 81: 7985.
  • 2
    Verani MS, George SE, Leon CA et al. Systolic and diastolic performance at rest and during exercise in heart transplant recipients. J Heart Lung Transplant 1988; 7: 145151.
  • 3
    Kao AC, Van Trigt P II, Shaeffer-McCall GS et al. Central and peripheral limitations to upright exercise in untrained cardiac transplant recipients. Circulation 1994; 89: 26052615.
  • 4
    Paulus WJ, Bronzwaer JG, Felice H, Kishan N, Wellens F. Deficient acceleration of left ventricular relaxation during exercise after heart transplantation. Circulation 1992; 86: 11751185.
  • 5
    Hosenpud JD, Pantely GA, Morton MJ et al. Lack of progressive “restrictive” physiology after heart transplantation despite intervening episodes of allograft rejection: comparison of serial rest and exercise hemodynamics one and two years after transplantation. J Heart Transplant 1990; 9: 119123.
  • 6
    Schulman DS, Herman BA, Edwards TD, Ziady G, Uretsky BF. Diastolic dysfunction in cardiac transplant recipients: an important role in the response to increased afterload. Am Heart J 1993; 125: 435442.
  • 7
    Greenberg ML, Uretsky BF, Reddy PS et al. Long-term hemodynamic follow-up of cardiac transplant patients treated with cyclosporine and prednisone. Circulation 1985; 71: 487494.
  • 8
    Donald DE, Shephard JT. Response to exercise in dogs with cardiac denervation. Am J Physiol 1963; 205: 494500.
  • 9
    Zile MR, Brutsaert DL. New concepts in diastolic dysfunction and diastolic heart failure: part II. Cirulcation 2002; 105: 15031508.
  • 10
    Kass DA, Bronzwaer JGF, Paulus WJ. What mechanisms underlie diastolic dysfunction in heart failure ? Circ Res 2004; 94: 15331542.
  • 11
    Amende I, Simon R, Seegers A et al. Diastolic dysfunction during acute cardiac allograft rejection. Circulation 1990; 81(2 Suppl):III66III70.
  • 12
    Valantine HA, Hatle LK, Appleton CP, Gibbons R, Popp RL. Variability of Doppler echocardiographic indexes of left ventricular filling in transplant recipients and normal subjects. J Am Soc Echocardiogr 1990; 3: 276284.
  • 13
    Hasenfuss G, Schillinger W, Lehnart SE et al. Relationship between Na+-Ca2+ exchanger protein levels and diastolic function of failing human myocardium. Circulation 1999; 99: 641648.
  • 14
    Cain BS, Medrum DR, Kyung SJ et al. Human SERCA2a levels correlate inversely with age in senescent human myocardium. J Am Coll Cardiol 1998; 32: 458467.
  • 15
    Vigneswaran WT, Rumberger JA, Rodeheffer RJ, Breen JF, McGregor CG. Ventricular remodelling after orthotopic cardiac transplantation. Mayo Clin Proc 1996; 71: 735742.
  • 16
    McAllister HA. Histologic grading of cardiac allograft rejection: a quantitative approach. J Heart Transplant 1990; 9: 277282.
  • 17
    Hullin R, Asmus F, Ludwig A, Hersel J, Boekstegers P. Subunit expression of the cardiac L-type calcium channel is differentially regulated in diastolic failure of the cardiac allograft. Circulation 1999; 100: 155163.
  • 18
    Aurigemma GP, Zile MR, Gaasch WH. Lack of relationship between Doppler indices of diastolic function and left ventricular pressure transients in patients with definite diastolic heart failure. Am Heart J 2004; 148: 530535.
  • 19
    Hay I, Rich J, Ferber P, Burkhoff D, Maurer MS. The role of impaired myocardial relaxation in the production of elevated left ventricular filling pressure. Am J Physiol Heart Circ Physiol 2004; 288: H1203H1208.
  • 20
    Schmitz L, Schneider MBE, Langer PE. Isovolumic relaxation time corrected for heart rate has a constant value from infancy to adolescence. J Am Soc Echocardiogr 2003; 16: 221222.
  • 21
    Fehske W, Niedeggen A, Oman H, Pizzulli L, Manz M, Lüderitz B. Effect of nisoldipine and diltiazem on the systolic and diastolic function of the left ventricle in patients with coronary artery disease. Z Kardiol 1994; 83: 5059.
  • 22
    Betocchi S, Piscione F, Losi MA et al. Effects of diltiazem on left ventricular systolic and diastolic function in hypertrophic cardiomyopathy. Am J Cardiol 1996; 78: 451457.
  • 23
    Hanno O, Bogdanov KY, Delcayre C et al. Reduced threshold for myocardial cell calcium intolerance in the rat with aging. Am J Physiol 1995; 269: H1607—H1612.
  • 24
    Prestle J, Dietrich S, Preuss M, Bieligk U, Hasenfuss G. Heterogenous transmural gene expression of calcium-handling proteins and natriuretic peptides in the failing human heart. Cardiovasc Res 1999; 43: 323331.
  • 25
    Schwinger RH, Böhm M, Schmidt U et al. Unchanged protein levels of SERCA II and phospholamban but reduced calcium uptake and Ca2+-ATPase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with non-failing hearts. Circulation 1995; 92: 32203228.
  • 26
    Periasamy M, Reed TD, Liu LH et al. Impaired cardiac performance in heterozygous mice with a null mutation in the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 (SERCA2a) gene. J Biol Chem 1999; 274: 22562262.
  • 27
    Limas CJ, Olivari MT, Benditt DG, Almquist A. Altered calcium uptake by the sarcoplasmic reticulum following cardiac transplantation in humans. Can J Cardiol 1987; 3: 215219.
  • 28
    Zvaritch E, Backx P, Jirik F et al. The transgenic expression of highly inhibitory monomeric forms of phospholamban in mouse hearts impairs cardiac contractility. J Biol Chem 2000; 275: 1498514991.
  • 29
    Loh E, Barnett JV, Feldman AM et al. Decreased adenylate cyclase activity and expression of Gs alpha in human myocardium after orthotopic cardiac transplantation. Circ Res 1995; 76: 852860.
  • 30
    Klein I, Ojamaa K. Thyroid hormone and the cardiovascular system. N Engl J Med 2001; 344: 501509.
  • 31
    Bilmen JG, Wootton WL, Michelangeli WL. The inhibition of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase by macrocyclic lactones and cyclosporine A. Biochem J 2002; 366: 255263.
  • 32
    Kogler H, Schott P, Toischer K et al. Novel role for brain natriuretic peptide to antagonize myocardial sarcoplasmic reticulum calcium ATPase expression. Circulation 2004; 110: III167.