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References

  • 1
    Adams DH, Neuberger JM. Treatment of acute rejection. Semin Liver Dis 1992; 12: 8088.
  • 2
    Neuberger J. Liver allograft rejection–Current concepts on diagnosis and treatment. J Hepatol 1995; 23 (Suppl 1): 5461.
  • 3
    Wiesner RH, Rakela J, Ishitani MB et al. Recent advances in liver transplantation. Mayo Clin Proc 2003; 78: 197210.
  • 4
    Clavien PA, Harvey PR, Strasberg SM. Preservation and reperfusion injuries in liver allografts. An overview and synthesis of current studies. Transplantation 1992; 53: 957978.
  • 5
    Lemasters JJ, Bunzendahl H, Thurman RG. Reperfusion injury to donor livers stored for transplantation. Liver Transpl Surg 1995; 1: 124138.
  • 6
    Gonzalez-Flecha B, Cutrin JC, Boveris A. Time course and mechanism of oxidative stress and tissue damage in rat liver subjected to in vivo ischemia-reperfusion. J Clin Invest 1993; 91: 456464.
  • 7
    Kumamoto Y, Suematsu M, Shimazu M et al. Kupffer cell-independent acute hepatocellular oxidative stress and decreased bile formation in post-cold-ischemic rat liver. Hepatology 1999; 30: 14541463.
  • 8
    Fondevila C, Busuttil RW, Kupiec-Weglinski JW. Hepatic ischemia/reperfusion injury–A fresh look. Exp Mol Pathol 2003; 74: 8693.
  • 9
    Essani NA, McGuire GM, Manning AM, Jaeschke H. Endotoxin-induced activation of the nuclear transcription factor kappa B and expression of E-selectin messenger RNA in hepatocytes, Kupffer cells, and endothelial cells in vivo. J Immunol 1996; 156: 29562963.
  • 10
    Essani NA, Fisher MA, Jaeschke H. Inhibition of NF-kappa B activation by dimethyl sulfoxide correlates with suppression of TNF-alpha formation, reduced ICAM-1 gene transcription, and protection against endotoxin-induced liver injury. Shock 1997; 7: 9096.
  • 11
    Le Moine O, Louis H, Stordeur P, Collet JM, Goldman M, Deviere J. Role of reactive oxygen intermediates in interleukin 10 release after cold liver ischemia and reperfusion in mice. Gastroenterology 1997; 113: 17011706.
  • 12
    Jaeschke H. Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Am J Physiol Gastrointest Liver Physiol 2003; 284: G15G26.
  • 13
    Lentsch AB, Kato A, Yoshidome H, McMasters KM, Edwards MJ. Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury. Hepatology 2000; 32: 169173.
  • 14
    Downward J. Mechanisms and consequences of activation of protein kinase B/Akt. Curr Opin Cell Biol 1998; 10: 262267.
  • 15
    Franke TF, Kaplan DR, Cantley LC. PI3K: Downstream AKTion blocks apoptosis. Cell 1997; 88: 435437.
  • 16
    Shah V, Kamath PS. Nitric oxide in liver transplantation: Pathobiology and clinical implications. Liver Transpl 2003; 9: 111.
  • 17
    Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 1999; 399: 601605.
  • 18
    Fulton D, Gratton JP, McCabe TJ et al. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 1999; 399: 597601.
  • 19
    Gratton JP, Morales-Ruiz M, Kureishi Y, Fulton D, Walsh K, Sessa WC. Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells. J Biol Chem 2001; 276: 3035930365.
  • 20
    Sessa WC, Garcia-Cardena G, Liu J et al. The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide. J Biol Chem 1995; 270: 1764117644.
  • 21
    Tugues S, Morales-Ruiz M, Fernandez-Varo G et al. Microarray analysis of endothelial differentially expressed genes in liver of cirrhotic rats. Gastroenterology 2005; 129: 16861695.
  • 22
    Fujio Y, Walsh K. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J Biol Chem 1999; 274: 1634916354.
  • 23
    Scotland RS, Morales-Ruiz M, Chen Y et al. Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion. Circ Res 2002; 90: 904910.
  • 24
    Hendrickson H, Chatterjee S, Cao S, Morales RM, Sessa WC, Shah V. Influence of caveolin on constitutively activated recombinant eNOS: Insights into eNOS dysfunction in BDL rat liver. Am J Physiol Gastrointest Liver Physiol 2003; 285: G652G660.
  • 25
    Tabet J, Garcia-Valdecasas JC, Net M et al. Evaluation of ischemic liver injury during graft procurement from non-heart-beating donor pigs. Transpl Proc 1997; 29: 34823483.
  • 26
    Valero R, Garcia-Valdecasas JC, Tabet J et al. Hepatic blood flow and oxygen extraction ratio during normothermic recirculation and total body cooling as viability predictors in non-heart-beating donor pigs. Transplantation 1998; 66: 170176.
  • 27
    Suzuki S, Toledo-Pereyra LH, Rodriguez FJ, Cejalvo D. Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. Transplantation 1993; 55: 12651272.
  • 28
    Morales-Ruiz M, Lee MJ, Zollner S et al. Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. J Biol Chem 2001; 276: 1967219677.
  • 29
    Morales-Ruiz M, Cejudo-Martin P, Fernandez-Varo G et al. Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic rats. Gastroenterology 2003; 125: 522531.
  • 30
    Brunet A, Bonni A, Zigmond MJ et al. Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor. Cell 1999; 96: 857868.
  • 31
    Cardone MH, Roy N, Stennicke HR et al. Regulation of cell death protease caspase-9 by phosphorylation. Science 1998; 282: 13181321.
  • 32
    Datta SR, Dudek H, Tao X et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997; 91: 231241.
  • 33
    Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 1999; 401: 8285.
  • 34
    Harada N, Hatano E, Koizumi N et al. Akt activation protects rat liver from ischemia/reperfusion injury. J Surg Res 2004; 121: 159170.
  • 35
    Matsui T, Tao J, Del Monte F et al. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation 2001; 104: 330335.
  • 36
    Cottart CH, Do L, Blanc MC et al. Hepatoprotective effect of endogenous nitric oxide during ischemia-reperfusion in the rat. Hepatology 1999; 29: 809813.
  • 37
    Wang Y, Mathews WR, Guido DM, Farhood A, Jaeschke H. Inhibition of nitric oxide synthesis aggravates reperfusion injury after hepatic ischemia and endotoxemia. Shock 1995; 4: 282288.
  • 38
    Yagnik GP, Takahashi Y, Tsoulfas G, Reid K, Murase N, Geller DA. Blockade of the l-arginine/NO synthase pathway worsens hepatic apoptosis and liver transplant preservation injury. Hepatology 2002; 36: 573581.
  • 39
    Geller DA, Chia SH, Takahashi Y, Yagnik GP, Tsoulfas G, Murase N. Protective role of the l-arginine-nitric oxide synthase pathway on preservation injury after rat liver transplantation. JPEN J Parenter Enteral Nutr 2001; 25: 142147.
  • 40
    Langle F, Steininger R, Waldmann E et al. Improvement of cardiac output and liver blood flow and reduction of pulmonary vascular resistance by intravenous infusion of l-arginine during the early reperfusion period in pig liver transplantation. Transplantation 1997; 63: 12251233.
  • 41
    Valero R, Garcia-Valdecasas JC, Net M et al. l-arginine reduces liver and biliary tract damage after liver transplantation from non-heart-beating donor pigs. Transplantation 2000; 70: 730737.
  • 42
    Kaizu T, Ikeda A, Nakao A et al. Donor graft adenoviral iNOS gene transfer ameliorates rat liver transplant preservation injury and improves survival. Hepatology 2006; 43: 464473.
  • 43
    Langle F, Roth E, Steininger R, Winkler S, Muhlbacher F. Arginase release following liver reperfusion. Evidence of hemodynamic action of arginase infusions. Transplantation 1995; 59: 15421549.
  • 44
    Roth E, Steininger R, Winkler S et al. l-arginine deficiency after liver transplantation as an effect of arginase efflux from the graft. Influence on nitric oxide metabolism. Transplantation 1994; 57: 665669.
  • 45
    Forstermann U. Endothelial NO synthase as a source of NO and superoxide. Eur J Clin Pharmacol 2006; 62 (Suppl 13): 512.