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Partial Bladder Transplantation with En Bloc Kidney Transplant—The First Case Report of a ‘Bladder Patch Technique’ in a Human
Article first published online: 29 FEB 2008
DOI: 10.1111/j.1600-6143.2008.02180.x
©2008 The Authors Journal compilation © 2008 The American Society of Transplantation and the American Society of Transplant Surgeons
Additional Information
How to Cite
Kato, T., Selvaggi, G., Burke, G., Ciancio, G., Zilleruelo, G., Hattori, M., Gosalbez, R. and Tzakis, A. (2008), Partial Bladder Transplantation with En Bloc Kidney Transplant—The First Case Report of a ‘Bladder Patch Technique’ in a Human. American Journal of Transplantation, 8: 1060–1063. doi: 10.1111/j.1600-6143.2008.02180.x
Publication History
- Issue published online: 14 APR 2008
- Article first published online: 29 FEB 2008
- Received 26 November 2007, revised 15 January 2008 and accepted for publication 17 January 2008
- Abstract
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Keywords:
- Bladder augmentation;
- en bloc transplant;
- kidney transplantation;
- pediatric renal transplantation
A child with severe congenital kidney and urinary tract abnormalities received a transplant of two kidneys en bloc with ureters connected to a patch of donor bladder, resulting in successful transplantation without reflux at 18 months follow-up.
Transplantation of the urinary bladder has not been reported in humans. We transplanted a portion of the donor bladder with an en bloc kidney graft in a 12-month-old girl. The child had a congenital hypoplastic single kidney with an ectopic ureteral opening into the vagina. Her native bladder was extremely small. Bilateral kidneys were transplanted en bloc with their ureters connected to a patch of the donor bladder, which encompassed the bilateral ureterovesical junctions (UVJs) (bladder patch technique). Approximately one-third of the donor bladder wall was used. The bladder patch reperfused well via blood supply from the ureters. Posttransplant cystoscopy with retrograde cystogram revealed a viable transplanted bladder with normal emptying of transplanted ureters. No reflux across the donor UVJs was seen in a voiding cystourethrogram. The child is doing well with normal renal function at 18-month follow-up.