It has been another exciting year in the field of transplantation. Since last year's Scientific Registry of Transplant Recipients (SRTR) Report on the State of Transplantation, new issues have emerged and new trends have been identified. The SRTR is very pleased that so many experts from around the country have again agreed to review the latest data submitted to the Organ Procurement and Transplantation Network (OPTN) and have produced the high-quality peer-reviewed articles that make up this seventh annual special issue you are now reading. The data underlying these papers can be found in the tables of the OPTN/SRTR Annual Report, published each year by the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services. For the first time, we have embedded the specific Annual Report table references in each article, so that you can more easily go to the source information at the SRTR web site ( Additional analyses have also been performed by the SRTR to illuminate important new areas, as part of our ongoing effort to identify emerging data trends in the field of transplantation.

This year, we brought together 47 nationally and internationally recognized experts to critically review and explain trends in solid organ transplantation in the United States over the past 10 years. We also offer two special focus articles on topics of particularly timely interest. The first provides a comprehensive explanation of the concept and methods recently developed by the SRTR for transplant centers to monitor their outcomes using the cumulative summation (CUSUM) technique. CUSUM is ideally suited as a quality improvement tool. The second article explains the evolution of liver net benefit calculations as the basis for a revision of deceased donor liver allocation policy in the United States. The concept of liver net benefit as a criterion for liver allocation has been adopted by the OPTN Liver and Intestinal Organ Transplantation Committee, which has been working with the SRTR as we refine this methodology toward eventual implementation. The SRTR team will continue to offer cutting-edge special focus articles like these each year.

The SRTR Report on the State of Transplantation is a project that brings together a group of talented and dedicated people. As the guest editor, I am very privileged to work with each of them. Dr. Philip Halloran, Editor-in-Chief of the American Journal of Transplantation, continues to strongly support our efforts and provides clear and very helpful guidance. Pamela Publicover at the AJT editorial office kept us on track once again through the entire peer-review process, ably assisted by Gillian Hughes. We have excellent and important relationships with Wiley-Blackwell, especially with Alison Labbate, Kate Heinle, Sharon Mathelus, Fadia Matouk and Cathy Krendel, each of whom has continued to facilitate the production and distribution of the report.

Our colleagues at the Division of Transplantation at HRSA are always extremely important partners in this effort. In particular, we are grateful to Richard Durbin, Chris McLaughlin, Monica Lin, Richard Laeng, Elizabeth Ortiz-Rios, Bernie Kozlovsky and Helen Li for their active participation, advice and encouragement. We would also like to express our thanks to James Burdick, who provided important and valuable input to the SRTR for many years.

Our 47 authors, representing every area of clinical transplantation, completed their tasks professionally, responsibly and on time. I am indebted to each of the authors for making and fulfilling their commitment to the SRTR Report on the State of Transplantation this year. Each of our lead authors was particularly outstanding.

This report simply wouldn't happen without the expertise, hard work and passion of my colleagues at the University of Michigan and the Arbor Research Collaborative for Health. I thank the principals of the SRTR project, Drs. Robert A. Wolfe (Principal Investigator), Friedrich K. Port, Alan B. Leichtman, Akinlolu O. Ojo, Susan Murray, Douglas E. Schaubel, Jack D. Kalbfleisch, John C. Magee, Randall S. Sung, D. Bradley Dyke and Panduranga S. Rao. Nearly all of the SRTR's analysts, programmers and administrative staff from the University of Michigan and Arbor Research contributed to this report, including Charlotte J. Arrington, Valarie B. Ashby, Andrew D. Barnes, David M. Dickinson, Melissa A. Fava, Mary K. Guidinger, Benjamin H. Guidinger, Sangeetha M. Krishnan, Craig D. Lake, Gregory N. Levine, Jack Liao, Keith P. McCullough, Emily E. Messersmith, Kathryn H. Meyer, Jeffrey Moore, Tiffani A. Pace, Katherine E. Pearson, Ann M. Rodgers, Erik C. Roys, Tempie H. Shearon, Sheetal A. Sonar, Diane E. Steffick, Randall L. Webb and James C. Welch.

A few people especially stand out. Katherine Pearson is the administrative project lead for the SRTR team. With her calm and thorough attention, she always had her finger on the pulse of this project. Andrew D. Barnes responded to requests for special analyses and prepared the hundreds of reference tables that form the basis for these articles, supplying drafts to authors and incorporating their feedback. Caroline A. Shevrin, who took over this year as the senior editor for the project, assumed her new role seamlessly, expertly, and with great enthusiasm. She was ably assisted by Jennifer L. McCready-Maynes and Shauna A. Leighton, who managed drafts and revisions of the articles from the editorial perspective, coordinated the peer-review process among coauthors, expertly edited text and graphics, and ensured that a uniform stylistic approach was applied to each manuscript. Their remarkable skills and attention to detail contributed greatly to each article.

This report is the product of hard work and dedication by everyone who participated in its creation. We hope that you find it informative and refer to it throughout the year.