Contributed equally to first authorship.
Adult Right-Lobe Living Liver Donors: Quality of Life, Attitudes and Predictors of Donor Outcomes
Article first published online: 16 APR 2009
© 2009 The Authors Journal compilation © 2009 The American Society of Transplantation and the American Society of Transplant Surgeons
American Journal of Transplantation
Volume 9, Issue 5, pages 1169–1178, May 2009
How to Cite
DuBay, D. A., Holtzman, S., Adcock, L., Abbey, S., Greenwood, S., Macleod, C., Kashfi, A., Jacob, M., Renner, E. L., Grant, D. R., Levy, G. A. and Therapondos, G. (2009), Adult Right-Lobe Living Liver Donors: Quality of Life, Attitudes and Predictors of Donor Outcomes. American Journal of Transplantation, 9: 1169–1178. doi: 10.1111/j.1600-6143.2009.02614.x
- Issue published online: 16 APR 2009
- Article first published online: 16 APR 2009
- Received 28 July 2008, revised 13 January 2009 and accepted for publication 08 February 2009
- Donor hepatectomy;
- living donor liver transplantation;
To refine selection criteria for adult living liver donors and improve donor quality of care, risk factors for poor postdonation health-related quality of life (HRQOL) must be identified. This cross-sectional study examined donors who underwent a right hepatectomy at the University of Toronto between 2000 and 2007 (n = 143), and investigated predictors of (1) physical and mental health postdonation, as well as (2) willingness to participate in the donor process again. Participants completed a standardized HRQOL measure (SF-36) and measures of the pre- and postdonation process. Donor scores on the SF-36 physical and mental health indices were equivalent to, or greater than, population norms. Greater predonation concerns, a psychiatric diagnosis and a graduate degree were associated with lower mental health postdonation whereas older donors reported better mental health. The majority of donors (80%) stated they would donate again but those who perceived that their recipient engaged in risky health behaviors were more hesitant. Prospective donors with risk factors for lower postdonation satisfaction and mental health may require more extensive predonation counseling and postdonation psychosocial follow-up. Risk factors identified in this study should be prospectively evaluated in future research.