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Mumps: Not an Innocent Bystander in Solid Organ Transplantation
Article first published online: 26 JUN 2009
DOI: 10.1111/j.1600-6143.2009.02732.x
© 2009 The Authors Journal compilation © 2009 The American Society of Transplantation and the American Society of Transplant Surgeons
Additional Information
How to Cite
Baas, M. C., Van Donselaar, K. A. M. I., Florquin, S., Van Binnendijk, R. S., Ten Berge, I. J. M. and Bemelman, F. J. (2009), Mumps: Not an Innocent Bystander in Solid Organ Transplantation. American Journal of Transplantation, 9: 2186–2189. doi: 10.1111/j.1600-6143.2009.02732.x
Publication History
- Issue published online: 20 AUG 2009
- Article first published online: 26 JUN 2009
- Received 06 January 2009, revised 12 April 2009 and accepted for publication 03 May 2009
- Abstract
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Keywords:
- Interstitial nephritis;
- kidney transplantation;
- mumps viral
A renal transplant recipient developed acute irreversible transplant failure due to interstitial nephritis caused by mumps.
Recently two major outbreaks of mumps have occurred: in the UK more than 56,000 cases were notified between 2004 and 2005, and in the United States, 6,584 cases were reported in 2006. Most patients were young healthy adults, in whom mumps normally has a benign course. Little is known about mumps in the immunocompromised patient. Here, we report a case of a 56-year renal transplant recipient who developed acute irreversible transplant failure due to interstitial nephritis caused by mumps. RNA of the mumps virus was detected in the urine as well as in a renal biopsy. In view of the ongoing presence of the mumps virus in the population, one should be aware of the possible occurrence of this infection in immunocompromised patients.